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Study to Improve the Treatment of Patients With Heart Failure by General Practitioners (TOPHU)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01662323
Recruitment Status : Completed
First Posted : August 10, 2012
Last Update Posted : November 14, 2012
Agis Zorgverzekeringen
Information provided by (Responsible Party):
Drs. Mark M J Valk, Julius Center

Brief Summary:
The purpose of this study is to determine whether it is possible to improve the care of general practitioners for patients with heart failure. The investigators try to reach that goal by training the GP's for 90 minutes in uptitrating the recommended medication according the guidelines. After 6 month the investigators ask the patients to fill out a questionary. The investigators ask them about their quality of live.

Condition or disease Intervention/treatment Phase
Heart Failure Behavioral: GP's treating HF according the dutch guidelines Phase 4

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 683 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Care Provider)
Primary Purpose: Treatment
Official Title: Therapy OPtimization Heart Failure Utrecht
Study Start Date : June 2009
Actual Primary Completion Date : June 2012
Actual Study Completion Date : June 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Heart Failure

Arm Intervention/treatment
Active Comparator: Training of the GP's, intervention
General practitioners are trained to diagnose and treat heart failure according the recommendations of the NHG-standard.
Behavioral: GP's treating HF according the dutch guidelines
Active Comparator: Controle
General practitioners giving care as usual to their heart failure patients.
Behavioral: GP's treating HF according the dutch guidelines

Primary Outcome Measures :
  1. proportion recommended medication for patients with heart failure [ Time Frame: up to 6 months ]
    the proportion patient who got at the end of the study the tree medicaments which should be prescribed to a patient with heart failure.

Secondary Outcome Measures :
  1. QoL [ Time Frame: up to 1 year ]
    Measurement of quality of live six months after uptitration of the recommended medication.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Do have a general practitioners diagnosis heart failure mentioned twice in the electronical medical file.

Exclusion Criteria:

  • Incapacitated patients with a life expectancy of less than 2 months
  • Seniles
  • Patients who do not speak the Dutch language

Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Drs. Mark M J Valk, assistant professor, Julius Center Identifier: NCT01662323     History of Changes
Other Study ID Numbers: TOPHU01
First Posted: August 10, 2012    Key Record Dates
Last Update Posted: November 14, 2012
Last Verified: November 2012
Keywords provided by Drs. Mark M J Valk, Julius Center:
Heart failure, general practitioner, medical therapy, quality of live
Additional relevant MeSH terms:
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Heart Failure
Heart Diseases
Cardiovascular Diseases