Measure Cardiac Output Using Ultrasound Dilution in Mechanically Ventilated Children
Post Cardiac Surgery
|Study Design:||Time Perspective: Prospective|
|Official Title:||Investigation of the Reliability to Measure Cardiac Output by a New Ultrasound Dilution Method in Mechanically Ventilated Children After Pediatric Cardiac Surgery|
- Measurement of cardiac output by a new ultrasound dilution method in mechanically ventilated children after pediatric cardiac surgery. [ Time Frame: Measurements are made during a patient's stay with insitu catheters. The expected average stay is 3-4 days. ] [ Designated as safety issue: No ]To compare cardiac outputs measured with this new ultrasound dilution method with flowmetry (perivascular probe) using ultrasound transit time measured directly on the aorta in children < 15 kg of weight. Also to assess reliability of COstatus measurements in pediatric patients.
|Study Start Date:||February 2010|
|Study Completion Date:||September 2011|
|Primary Completion Date:||September 2011 (Final data collection date for primary outcome measure)|
The thermodilution technique with a pulmonary artery catheter has been the standard in adult patients for cardiac output measurement. However, using pulmonary artery catheter remains a major clinical problem in children due to technical and size constraints.
COstatus measures changes in blood ultrasound velocity in an extracorporeal AV loop caused by body-temperature isotonic saline injected into the central vein and calculates cardiac output derived from a dilution curve.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01662141
|Children Hospital, BUS, BIVA|
|Lund, Sweden, SE-221 85|
|Principal Investigator:||Lars Lindberg, MD, PhD||University Hospital in Lund|