Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis
|ClinicalTrials.gov Identifier: NCT01659619|
Recruitment Status : Completed
First Posted : August 8, 2012
Last Update Posted : February 21, 2013
Erythromycin has a prokinetic effect through Motilin receptor. It evokes migrating motor complex with longer and stronger contraction.
In patients with upper gastrointestinal bleeding, It has been shown that erythromycin could clear the stomach of blood, so visual examination could be improved.
Frequent food stasis is encounted when we examine patients with subtotal gastrectomy. It is postulated that erythromycin reduce food stasis and help to improve endoscopy in these cases.
|Condition or disease||Intervention/treatment||Phase|
|Subtotal Gastrectomy Stomach Cancer||Drug: Erythromycin||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||114 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis : Randomized and Prospective Study|
|Study Start Date :||April 2012|
|Primary Completion Date :||October 2012|
|Study Completion Date :||October 2012|
125mg in normal saline single use infusion for 5 min.
|No Intervention: saline|
- degree of food stasis [ Time Frame: when endoscopy is performed. ]ref> Gastric Cancer (2002) 5: 83-89
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01659619
|Korea, Republic of|
|Seoul St. Mary hospital|
|Seoul, Korea, Republic of|
|Principal Investigator:||Myung-Gyu Choi, M.D.||Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea|