Imaging Parameters to Predict Future Vertebral Fracture in Osteoporosis
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|ClinicalTrials.gov Identifier: NCT01653873|
Recruitment Status : Unknown
Verified January 2014 by National Taiwan University Hospital.
Recruitment status was: Recruiting
First Posted : July 31, 2012
Last Update Posted : January 24, 2014
|Condition or disease|
Vertebroplasty is considered one of the alternatives for the treating of spine compression fracture associated with pain especially for those patients with osteoporosis. However, after vertebroplasty, the compliance of the bone becomes stronger than the adjacent vertebrae that is not treated. So there is always a consideration of future fracture of the adjacent vertebral bodies after vertebroplasty done on certain body. In this study, we try to follow the patients (5 years) to see if the adjacent vertebral bodies are prone to have fracture than the others away from the site of vertebroplasty.Then we try to find out the image biomarkers to predict the future fracture in the vertebral bodies. The should be done with CT scan raw data, analysis with different algorithms.
Inclusion criteria; patients with osteoporosis and receiving vertebroplasty and with secondary fracture occurring in other spine exclusion criteria: No second vertebral body fracture occurred. Primary measurement: the time and location of the 2nd fracture secondary measurement: the imaging biomarkers from CT scan.
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Official Title:||to Compare the Efficacy of Parameters From Different Imaging Modality in Predicting the Risk of Future Vertebral Compression Fracture in Osteoporotic Patients.|
|Study Start Date :||July 2012|
|Estimated Primary Completion Date :||December 2016|
|Estimated Study Completion Date :||December 2017|
- fracture [ Time Frame: 5 years ]2nd fracture within 5 years
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01653873
|Contact: Hon-man Liu, MD, MBA||886-2-23123456 ext email@example.com|
|National Taiwan University Hospital||Recruiting|
|Taipei, Taiwan, 10016|
|Contact: Hon-Man Liu, MD, MBA 886-2-23123456 ext 70329 firstname.lastname@example.org|
|Principal Investigator: Hon-Man Liu, MD, MBA|
|Principal Investigator:||Hon-Man Liu, MD, MBA||National Taiwan University Hospital|