Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
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A DNA hypermethylation of the gene locus SHOX2 can be frequently found in lung cancer tissue. The purpose of this study is to determine whether the assessment of the hypermethylation level of SHOX2 in specimens obtained by endosonographic guided bronchoscopy makes a contribution to lung cancer staging.
Condition or disease
Lung Cancer With Mediastinal Lymph Node Involvement
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Ages Eligible for Study:
18 Years to 90 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with proven or suspcted lung cancer and enlarged mediastinal or hilar lymph nodes
clinical diagnosis of lung cancer
enlarged mediastinal or hilar lymph nodes (>10 mm)
clinical condition which excludes general anesthesia