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Ultrasound Use for Difficult Lumbar Punctures in Pediatric Oncology Patients

This study has been terminated.
(We were unable to recruit subjects for this study.)
Information provided by (Responsible Party):
Tarun Bhalla, MD, Nationwide Children's Hospital Identifier:
First received: July 12, 2012
Last updated: February 4, 2015
Last verified: February 2015
Hematology-oncology patients may require frequent lumbar puncture for diagnosis, assessment and therapy. When LP is difficult, the patient may endure multiple attempts, prolonged anesthesia time, and with failure of LP may require fluoroscopy-guidance with associated radiation exposure. This investigation will evaluate lumbar punctures performed in the intraoperative setting by oncologists with ultrasound guidance performed by the anesthesiologist in the leukemic pediatric population. The investigators hypothesis is that anesthesiologist guided ultrasound assistance will decrease intraoperative time, number of attempts and need to have the procedure done with fluoroscopy minimizing radiation exposure.

Condition Intervention
Leukemia Procedure: Ultrasound

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Ultrasound Imaging Facilitates Lumbar Punctures in Pediatric Oncology Patients With Difficult Surface Landmarks and/or a History of Difficult Lumbar Puncture

Resource links provided by NLM:

Further study details as provided by Tarun Bhalla, MD, Nationwide Children's Hospital:

Primary Outcome Measures:
  • Number of punctures [ Time Frame: 1 day ]
    Number of punctures required to obtain cerebral spinal fluid.

Enrollment: 3
Study Start Date: July 2012
Study Completion Date: May 2014
Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Ultrasound Procedure: Ultrasound
Ultrasound guidance for difficult lumbar punctures in the leukemic pediatric population.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All patients undergoing LP as per Heme-Onc clinic who have been deemed to be difficult LP placements.

Exclusion Criteria:

  • Patients having concomitant procedures (bone marrow bx, etc.)
  Contacts and Locations
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Please refer to this study by its identifier: NCT01643291

United States, Ohio
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Sponsors and Collaborators
Nationwide Children's Hospital