Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01643239 |
Recruitment Status
:
Completed
First Posted
: July 18, 2012
Last Update Posted
: February 28, 2013
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Cerebral Palsy | Other: Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm Other: Hospital-based mCIT Other: Hospital-based TR | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 60 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double (Participant, Care Provider) |
Primary Purpose: | Treatment |
Official Title: | Effects of Forms of Modified Constraint-induced Therapy on Functional Performance of Upper Extremity in Children With Cerebral Palsy With Asymmetric Motor Impairments: A Follow up Study of Kinematic and Clinical Analyses |
Study Start Date : | August 1996 |
Actual Primary Completion Date : | September 2012 |
Arm | Intervention/treatment |
---|---|
Experimental: Hospital-based mCIT with individualized intervention
Hospital-based modified constraint-induced therapy(mCIT)
|
Other: Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm
the mCIT group with individualized intervention
Other Name: Hospital-based modified constraint-induced therapy(mCIT)
|
Experimental: Hospital-based mCIT with group therapy
Hospital-based modified constraint-induced therapy(mCIT)
|
Other: Hospital-based mCIT
the mCIT group with individualized intervention
Other Name: Hospital-based modified constraint-induced therapy(mCIT)
|
Hospital-based TR
Hospital-based traditional rehabilitation (TR)
|
Other: Hospital-based TR
OT or PT or therapist-based training
Other Name: Hospital-based traditional rehabilitation (TR)
|
- Kinematic assessment [ Time Frame: up to six years ]An analysis program coded by LabVIEW (National Instruments, Inc., Austin, TX) language was used to process the kinematic data. The variables of reaction time (sec), normalized movement time (sec/mm), normalized total displacement (unit), joint ranges recruitment (normalized shoulder flexion angle, normalized elbow flexion; degree/mm) angle, and normalized maximum shoulder abduction angle), and maximum shoulder and elbow cross correlation were collected.
- Clinical measures at the motor quality and performance include Motor Activity Log (MAL), Bruininks-Oseretsky Test of Motor Proficiency (BOTMP), and Peabody-Developmental Motor Scales (PDMS-II) [ Time Frame: up to six years ]The clinical tools used in this study measure the intervention impact on bimanual coordination and unilateral performance of upper extremity.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 4 Years to 10 Years (Child) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- clinical diagnosis of spastic CP
- age between 4 and 10 years old
- shoulder flexion of the affected upper limb more than 90 degrees, elbow extension over 160 degrees, wrist extension to 10 degrees at least, and fingers full flexion to 10 degrees at least
- basic balance ability: sitting on the chair without arm support; feet stay on the floor consistently; performing the affected upper limb movement without losing balance
- ability to follow simple oral commands
- no related musculoskeletal surgery of the affected upper limb
- not have injected the Botox into the affected upper extremity during the past 6 months
- no visual or auditory disability

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01643239
Taiwan | |
Chang Gung Memorial Hospital | |
Kwei-shan, Toayuan county, Taiwan |
Principal Investigator: | Ching-yi Wu, ScD | Department of Occupational Therapy, Chang Gung Univ. |
Responsible Party: | Chang Gung Memorial Hospital |
ClinicalTrials.gov Identifier: | NCT01643239 History of Changes |
Other Study ID Numbers: |
94-1052B |
First Posted: | July 18, 2012 Key Record Dates |
Last Update Posted: | February 28, 2013 |
Last Verified: | February 2013 |
Keywords provided by Chang Gung Memorial Hospital:
Modified constraint-induced therapy Children with cerebral palsy Kinematic analysis Group therapy |
Additional relevant MeSH terms:
Paralysis Cerebral Palsy Neurologic Manifestations Nervous System Diseases |
Signs and Symptoms Brain Damage, Chronic Brain Diseases Central Nervous System Diseases |