ClinicalTrials.gov
ClinicalTrials.gov Menu

The Effect of Thyme and Sumac on the Thermic Effect of Food and Comparison Between Warm and Cold Temperament People

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01643096
Recruitment Status : Unknown
Verified July 2012 by Tehran University of Medical Sciences.
Recruitment status was:  Not yet recruiting
First Posted : July 17, 2012
Last Update Posted : July 17, 2012
Sponsor:
Information provided by (Responsible Party):
Tehran University of Medical Sciences

Brief Summary:
The purpose of this study is to determine the effect of Zataria multiflora Boiss and Sumac on the thermic effect of food, activity of sympathetic - parasympathetic system: comparison between warm and cold temperament people.

Condition or disease Intervention/treatment Phase
Effects of; Food, Allergic Other: Zataria multiflora Boiss Other: Sumac Not Applicable

Detailed Description:

Human body needs to energy in order to preserve life.There are three forms of energy consumption at body, consumption at baseline or resting, consumption at energy expenditure for Thermic effect of food and energy is spent in physical activity.Also from the perspective of traditional medicine, cold and warm natured people are determined based on certain mental and physical protests.

There are different temperament not only in Traditional Iranian Medicine, but in traditional Chinese medicine, Indian, Greek, Arabic, Romanian, and there are European.As various factors on the basal metabolism and thermic effect of food , also are several factors such as age, sex, physical condition of the environment that have an impact on individual temperament.

Since the protests seem warm and cool temperament and factors affecting on their basal metabolic rate and thermogenesis so that food may explain the relationship between warm and cold temperament to mind is the basal metabolism; It seems those are hot temperament, their basal metabolic rate is higher BMR than normal and those who are cold temperament, have a lower BMR.

On the other hand seems that thermic effect of food in people who have hot temperament is higher than thermic effect of food in people who have cold temperament.

So that we need to use of two nutrient foods, in this way we consided the multiple criteria and then were selected sumac and thyme.

On the other hand, in order to study possible mechanisms affecting basal metabolism, thermogenesis of food, according to previous studies and also matches that there are between sympathetic - parasympathetic and thyroid function, with symptoms of cold and warm temperament there, checking of activity of these organs seems necessary.

Because to maintain basal metabolic rate is essential for human life, so that each factor in order to better understand these is helpful to human life.And the need for such study makes clear;Through this step help toward improving public health


Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Investigator)
Study Start Date : August 2012
Estimated Primary Completion Date : August 2013
Estimated Study Completion Date : August 2014

Arm Intervention/treatment
sumac
Thermic effect of food of Sumac and comparison between hot and cold temperament people
Other: Sumac
Thermic effect of food of Sumac and comparison between hot and cold temperament people
Other Name: sumach
Zataria multiflora Boiss
Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people
Other: Zataria multiflora Boiss
Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people
Other Name: Thyme



Primary Outcome Measures :
  1. Thermic Effect of Food (TEF) [ Time Frame: Change from baseline to 4 hours And repeated 1 week later ]
    kilocalorie(kcal) and by indirect calorimetery


Secondary Outcome Measures :
  1. activity of sympathetic - parasympathetic system(Epinephrine, Norepinephrine, Cortisol) [ Time Frame: Change from baseline to 4 hours And repeated 1 week later ]
    ng/ml



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion criteria:

  • Age 18 to 40 years
  • Having to suffer any ill health and lack of attention to history and physical examination
  • Willing to cooperate with the project

Exclusion Criteria:

  • Catching any disease.
  • Use of specific dietary patterns such as vegetarianism
  • Having a BMI outside the normal range
  • Use of any drugs or supplements in past month
  • Allergic reaction to food allergy and non-prescription
  • An unwillingness to cooperate in any of the stages of implementation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01643096


Locations
Iran, Islamic Republic of
Tehran University of Medical Sciences Not yet recruiting
Tehran, Iran, Islamic Republic of
Contact: Dorosty Motlagh, PhD    (+98) 21 88951395    dorostim@sina.tums.ac.ir   
Contact: Mohammadi Farsani    (+98) 21 88974462    mohammadigh53@gmail.com   
Sponsors and Collaborators
Tehran University of Medical Sciences
Investigators
Principal Investigator: Ahmadreza Dorosty Motlagh, PhD Tehran University of Medical Sciences, tehran, iran

Responsible Party: Tehran University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01643096     History of Changes
Other Study ID Numbers: 90-04-27-15366
First Posted: July 17, 2012    Key Record Dates
Last Update Posted: July 17, 2012
Last Verified: July 2012

Keywords provided by Tehran University of Medical Sciences:
Zataria multiflora Boiss Sumac TEF temperament