Computerized Attention Training for Individuals With Acquired Brain Injury
|ClinicalTrials.gov Identifier: NCT01641432|
Recruitment Status : Completed
First Posted : July 16, 2012
Last Update Posted : July 22, 2014
|Condition or disease||Intervention/treatment||Phase|
|Acquired Brain Injury Stroke Hemispatial Neglect||Behavioral: Tonic and Phasic Attention Training Behavioral: Active Comparator||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||27 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Care Provider)|
|Official Title:||Computerized Cognitive Treatment of Vigilance Deficits in Individuals With Acquired Brain Injury|
|Study Start Date :||July 2011|
|Actual Primary Completion Date :||July 2013|
Computerized Tonic and Phasic Attention training consisting of visual, auditory, and spatial stimuli that requires sustained attention (24 minutes). Training is followed by a computerized cognitive exercise (12 minutes).
Behavioral: Tonic and Phasic Attention Training
The Tonic and Phasic Alertness treatment task (TAPAT) consist of two consecutive rounds of a 12-minute continuous performance task in which continually varying, rich visual (e.g., scenes, objects, faces) or auditory stimuli (tones or complex sounds) are briefly displayed and participants are required to respond via a button press when they see a non-target item (90% of trials) or withhold button-press responding when the item is a pre-determined target item (10% of trials). Presentation of the target item is non-predictive and infrequent, disallowing the development of an executive strategy. Participants simply sustain attention to the task over a prolonged period of time (tonic attention), ignoring distractions, and inhibiting the pre-potent motor response when they see a target item (phasic attention).
Following the 24 minutes of TAPAT treatment participants will undergo one additional computer-based cognitive exercise, Multiple Object Tracking (MOT), for an additional 12 minutes.
Active Comparator: Active Comparator
Computerized conventional board-games that lack the therapeutic effect of the TAPAT exercises. Active control has stimulus parameters similar to the TAPAT exercises (eg. stimuli is presented on the computer, participant responses are collected, session time and improvement is measured).
Behavioral: Active Comparator
Computer games chosen from a list of progressive visual/audiovisual games from the top-100 game list: sporcle.com. Training duration will be similar to that of experimental training.
- Attention and Memory [ Time Frame: 6 months ]Percent change on standardized measures of attention and executive function (all participants) using the ASCAN, Attentional Blink, Attention Capture Task, Landmark task, Conjunction Search task, SART, Verbal Fluency, CVLT-II, D-KEFS Stroop, and LNS assessments.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01641432
|United States, California|
|Brain Plasticity Institute|
|San Francisco, California, United States, 94104|