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Development of Method of Fructose Identification in Urine to Detect the Viral Infection

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ClinicalTrials.gov Identifier: NCT01638312
Recruitment Status : Completed
First Posted : July 11, 2012
Results First Posted : October 5, 2015
Last Update Posted : October 5, 2015
Sponsor:
Information provided by (Responsible Party):
Kaohsiung Medical University Chung-Ho Memorial Hospital

Study Description
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Brief Summary:
The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification and its implementation to detect the viral infection in early stage. There will be 20 samples from the HIV-infected patients and 30 samples from the heath controls. The study will collect 10ml urine and examined fructose and fructose-diphosphate using the polarographic method.

Condition or disease
Human Immunodeficiency Virus

Detailed Description:
The goal of this research is the attempt to implement a new research method based on modern electrochemistry successes, in particular the development of the polarographic method of fructose and fructose diphosphate identification and its implementation to detect the viral infection in early stage.

Study Design
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Study Type : Observational
Actual Enrollment : 50 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: The Development of Fast and Simple Method of Fructose Identification in Urine to Detect the Viral Infection in Early Stage
Study Start Date : June 2011
Actual Primary Completion Date : May 2013
Actual Study Completion Date : May 2013

Resource links provided by the National Library of Medicine

Drug Information available for: Fructose
U.S. FDA Resources

Groups and Cohorts
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Group/Cohort
HIV infection patient and health people
The study does not have intervention


Outcome Measures
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Primary Outcome Measures :
  1. Fructose Identification in Urine to Detect the Viral Infection : Number of Participants With Positive and Negative Waveform [ Time Frame: Participants provided urine samples once ]

    This detection technique, after a viral infection caused by the use of cell pathological changes and urine metabolic waste - fructose concentration, derivatives.Health News voltage changes to detect viral pathogens of activity and virulence. Because viral infection caused by the voltage change has its typical, So you can use voltage measurements to calibrate the presence and activity of a viral infection.

    1.How to interpretation the data The gap between values on X-axis is σ, and 50 is a reference to the center position. For example, the sample maybe contain with HIV virus if σ≧10 units.

    σ≧10 abnormal positive (+) σ＜10 normal negative (-)



Biospecimen Retention:   None Retained
urine

Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
the person who has HIV infection
Criteria

Inclusion Criteria:

  • HIV infection

Exclusion Criteria:

  • who are in highly active antiretroviral therapy(HARRT) therapy
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01638312


Locations
Taiwan
Tropical Medicine Center, Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung, Taiwan, 807
Sponsors and Collaborators
Kaohsiung Medical University Chung-Ho Memorial Hospital
Investigators
Principal Investigator: JihJin Tsai, MD The Medicines Company
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Responsible Party: Kaohsiung Medical University Chung-Ho Memorial Hospital
ClinicalTrials.gov Identifier: NCT01638312     History of Changes
Other Study ID Numbers: KMUH-IRB-20110188
First Posted: July 11, 2012    Key Record Dates
Results First Posted: October 5, 2015
Last Update Posted: October 5, 2015
Last Verified: September 2012

Keywords provided by Kaohsiung Medical University Chung-Ho Memorial Hospital:
HIV, fructose

Additional relevant MeSH terms:
Acquired Immunodeficiency Syndrome
HIV Infections
Immunologic Deficiency Syndromes
Virus Diseases
Immune System Diseases
Lentivirus Infections
 Retroviridae Infections
RNA Virus Infections
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Slow Virus Diseases