NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)
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ClinicalTrials.gov Identifier: NCT01633671 |
Recruitment Status
:
Completed
First Posted
: July 4, 2012
Last Update Posted
: July 6, 2012
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Condition or disease |
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Pulmonary Embolism Pulmonary Embolism Without Mention of Acute Cor Pulmonale |
In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms.
Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.
Study Type : | Observational |
Actual Enrollment : | 44 participants |
Observational Model: | Case Control |
Time Perspective: | Retrospective |
Official Title: | NT-proBNP: a Useful Tool for the Detection of Acute Pulmonary Artery Embolism in Post-surgical Patients |
Study Start Date : | November 2008 |
Actual Primary Completion Date : | December 2011 |
Actual Study Completion Date : | December 2011 |

Group/Cohort |
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Suspected APE
Post-surgical patients with clinically suspected acute pulmonary embolism
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- Acute pulmonary embolism: CT-proof yes vs. no [ Time Frame: 1 hour after onset of clinical symptoms ]

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Ages Eligible for Study: | Child, Adult, Senior |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
all patients referred to the ICU with suspected APE
Exclusion Criteria:

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01633671
Germany | |
University of Ulm, Michelsberg anaesthesiologic ICU | |
Ulm, Baden-Wuerttemberg, Germany, 89075 |
Study Chair: | Claus M Muth, MD | Dept. of Anesthesiology, Div. of Emergency medicine, University hospital Ulm, 89075 Ulm, Germany | |
Principal Investigator: | Bernd E Winkler, MD | Dept. of Anesthesiology, University hospital Ulm, 89075 Ulm, Germany |
Responsible Party: | Claus-Martin Muth, Claus-Martin Muth, MD, PhD - Head of the Department of Emergency Medicine, University of Ulm |
ClinicalTrials.gov Identifier: | NCT01633671 History of Changes |
Other Study ID Numbers: |
ana-ulm-ntprobnp-288/11 |
First Posted: | July 4, 2012 Key Record Dates |
Last Update Posted: | July 6, 2012 |
Last Verified: | July 2012 |
Keywords provided by Claus-Martin Muth, University of Ulm:
Misadventures to Patients During Surgical and Medical Care Pulmonary Embolism Without Acute Cor Pulmonale Pulmonary Embolism Without Mention of Acute Cor Pulmonale |
Additional relevant MeSH terms:
Embolism Pulmonary Embolism Pulmonary Heart Disease Embolism and Thrombosis Vascular Diseases |
Cardiovascular Diseases Lung Diseases Respiratory Tract Diseases Heart Diseases |