Zinc Absorption From Biofortified Rice
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ClinicalTrials.gov Identifier: NCT01633450 |
Recruitment Status
:
Completed
First Posted
: July 4, 2012
Last Update Posted
: June 7, 2013
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Healthy | Other: Zinc biofortified rice Other: Rice extrinsically fortified with zinc | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 16 participants |
Allocation: | Randomized |
Intervention Model: | Crossover Assignment |
Masking: | Single (Participant) |
Official Title: | Bioavailability of Zinc From Rice Biofortified With 70Zn and Rice Extrinsically Labeled With 70Zn in Young Adults: a Randomized, Single-blind Study |
Study Start Date : | June 2012 |
Actual Primary Completion Date : | August 2012 |
Actual Study Completion Date : | October 2012 |
Arm | Intervention/treatment |
---|---|
Experimental: Zinc biofortified rice |
Other: Zinc biofortified rice
1.12 mg zinc per meal
|
Active Comparator: Rice extrinsically fortified with zinc |
Other: Rice extrinsically fortified with zinc
1.12 mg zinc per meal
|
- Fractional absorption of zinc [ Time Frame: 33 days ]Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.

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Ages Eligible for Study: | 18 Years to 45 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Male or female of 18 to 45 years old
- Body Mass Index in the range of 19 to 25
- No mineral and vitamin supplements two weeks prior to the study and during the whole duration of the study
Exclusion Criteria:
- Any metabolic, gastrointestinal or chronic disease (according to the subjects own statement)
- Long-term medication during the whole study (except for contraceptives)
- Pregnancy
- Lactation
- Intention to become pregnant during the course of the study
- Lack of safe contraception
- Consumption of mineral and vitamin supplements within 2 weeks prior to 1st - Earlier participation in any nutrition study using Zn stable isotopes as well as participation in any other clinical study within the last 30 days and during this study

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01633450
Switzerland | |
ETH Zurich | |
Zurich, Switzerland |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Prof. Michael B. Zimmermann, Prof, Swiss Federal Institute of Technology |
ClinicalTrials.gov Identifier: | NCT01633450 History of Changes |
Other Study ID Numbers: |
HNL/CTC12-Reis |
First Posted: | July 4, 2012 Key Record Dates |
Last Update Posted: | June 7, 2013 |
Last Verified: | June 2013 |
Additional relevant MeSH terms:
Zinc Trace Elements Micronutrients Growth Substances Physiological Effects of Drugs |