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Analysis of Risk Factors for Death After Blunt Traumatic Rupture of the Thoracic Aorta

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ClinicalTrials.gov Identifier: NCT01632774
Recruitment Status : Completed
First Posted : July 3, 2012
Last Update Posted : July 3, 2012
Sponsor:
Information provided by (Responsible Party):
University of Zurich

Brief Summary:
Aortic injuries after blunt thoracic trauma are compared to the great incidence of accidents relatively rare, but potentially serious leading to death at scene in most of the cases. The study was undertaken to delineate mortality and its risk factors on three different levels (pre-hospital, in-hospital and overall). Between 1990 and 2003, all consecutive patients and victims with traumatic aortic rupture were retrospectively analyzed by reviewing hospital and autopsy records.

Condition or disease
Aortic Rupture

Detailed Description:
During the study period of 14 years (January 1990 to December 2003), all consecutive cases with traumatic rupture of the thoracic aorta being reported in the greater area of Zurich with about one million inhabitants were included in the present study. Related to the final outcome, patient data were drawn either from medical reports from the University Hospital of Zurich, which is a tertiary care teaching hospital and level I trauma center for the eastern part of Switzerland, or from autopsy reports from the Institute of Forensic Medicine of the University of Zurich, respectively. The latter group includes all patients, who died on the scene, in a assigning primary care hospital or on the way to the University Hospital of Zurich. In Switzerland, the criteria used for performing a full autopsy after a blunt traumatic death include all cases in which the events leading to the death are unclear or in which the cause of death is the result of suicide or extrinsic harm. Both, deaths at the scene and in-hospital deaths were included in the study.

Study Type : Observational
Actual Enrollment : 85 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Analysis of Risk Factors for Death After Blunt Traumatic Rupture of the Thoracic Aorta
Study Start Date : January 1990
Actual Primary Completion Date : December 2003
Actual Study Completion Date : December 2003

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Tears
U.S. FDA Resources





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Ages Eligible for Study:   16 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Hospitalized patients Patients who died at the scene
Criteria

Inclusion criteria:

  • During the study period of 14 years (January 1990 to December 2003), all consecutive cases with traumatic rupture of the thoracic aorta being reported in the greater area of Zurich with about one million inhabitants were included in the present study

Exclusion criteria:

  • Non-traumatic aortic rupture
  • Non-traumatic aortic dissection

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01632774


Locations
Switzerland
University Hospital Zurich, Division of Internal Medicine
Zurich, ZH, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Investigators
Principal Investigator: Daniel Franzen, MD University Hospital Zurich, Division of Internal Medicine

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: University of Zurich
ClinicalTrials.gov Identifier: NCT01632774     History of Changes
Other Study ID Numbers: TAR
First Posted: July 3, 2012    Key Record Dates
Last Update Posted: July 3, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Rupture
Aortic Rupture
Wounds and Injuries
Aneurysm, Ruptured
Aneurysm
Vascular Diseases
Cardiovascular Diseases
Aortic Aneurysm
Aortic Diseases