Caloric Stimulation on Cerebral Blood Flow
|ClinicalTrials.gov Identifier: NCT01629901|
Recruitment Status : Completed
First Posted : June 28, 2012
Last Update Posted : March 21, 2017
|Condition or disease||Intervention/treatment||Phase|
|Healthy Volunteer||Device: ThermoNeuroModulation (TNM) Device||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Effect of Vestibular Stimulation on Cerebral Blood Flow|
|Study Start Date :||June 2012|
|Actual Primary Completion Date :||March 2015|
|Actual Study Completion Date :||April 2015|
Device: ThermoNeuroModulation (TNM) Device
- Changes in cerebral blood flow [ Time Frame: 20 minutes ]Changes in cerebral blood flow will be quantified through the use of bilateral transcranial Doppler (TCD). The baseline TCD of three vessels will be compared with measurements taken at 30 second intervals for 5 minutes after caloric stimulation.
- Alterations in EEG readings [ Time Frame: 40 minutes ]EEG readings occurring between baseline, active CVS induction, and post-CVS induction periods will be assessed to identify and characterize alterations in the readings.
- Alterations in regional cerebral brain flow (rCBF) [ Time Frame: 40 minutes ]A standard noninvasive near infrared spectroscopy system will be used to look for any alterations in rCBF induced by CVS treatment.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01629901
|United States, North Carolina|
|Duke University Medical Center|
|Durham, North Carolina, United States, 27710|
|Principal Investigator:||Daniel Laskowitz, MD||Duke University|