Disability and Quality of Life in Patients With Lymphatic Filariasis in Rural Southern India
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|ClinicalTrials.gov Identifier: NCT01629771|
Recruitment Status : Completed
First Posted : June 28, 2012
Results First Posted : August 2, 2013
Last Update Posted : March 20, 2014
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||72 participants|
|Observational Model:||Case Control|
|Official Title:||Disability and Quality of Life in Patients With Lymphatic Filariasis in Rural Southern India|
|Study Start Date :||May 2012|
|Actual Primary Completion Date :||June 2012|
|Actual Study Completion Date :||June 2012|
|Patients without Lymphatic Filariasis|
- Dermatology Life Quality Index (DLQI) Domain Scores [ Time Frame: Assessed after enrollment ]The DLQI is a 10-item questionnaire measuring skin-specific quality of life through six domains: Symptoms & Feelings, Daily Activities, Leisure, Work & School, Personal Relationships, and Treatment. Symptoms & Feelings, Daily Activities, Leisure, and Personal Relationships are each scored from 0 to 3, where 0 is associated with no effect on a patient's life, and 3 is associated with a large effect on a patient's life. Work & School and Treatment are each scored from 0 to 3, where 0 is associated with no effect on a patient's life, and 6 is associated with a large effect on a patient's life.
- Lymphatic Filariasis-Specific Quality of Life (LFSQQ) Domain Scores [ Time Frame: Assessed after enrollment ]The LFSQQ was developed to assess quality of life in subjects with lymphatic filariasis through seven domains: Mobility, Self-Care, Usual Activities, Disease Burden, Pain/Discomfort, Psychological Health, and Social Participation. Items are scored on a 5-point scale (no problem, mild, moderate, severe, most severe), and scores for each domain are calculated based on the number of questions answered and the raw scores. Scores for each domain range from 0 to 100, where 0 is associated with a worse quality of life and 100 is associated with a better quality of life.
- World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) Domain Scores [ Time Frame: Assessed after enrollment ]The WHODAS 2.0 is a generic health and disability assessment tool that describes effects of disease on six domains: Cognition, Mobility, Self-Care, Getting Along, Life Activities, and Participation in Society. Responses are measured on a 5-point scale from 1 (no difficulty) to 5 (extreme difficulty or cannot do). Scores are calculated using a WHO SPSS 36 version syntax for employed subjects and a WHO SPSS 32 version syntax for unemployed subjects. Scores for each domain range from 0 to 100, where 0 is associated with no impairment of health status, and 100 is associated with a greater impairment of health status.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01629771
|United States, Illinois|
|Northwestern University Department of Dermatology|
|Chicago, Illinois, United States, 60611|
|Institute of Applied Dermatology|
|Kasaragod district, Kerala, India|
|Principal Investigator:||Roopal Kundu, MD||Northwestern University|