Autoantibodies Against Specific Cytokines in Adults With Severe Mycobacterial Infection

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01628744
Recruitment Status : Unknown
Verified June 2012 by China Medical University Hospital.
Recruitment status was:  Recruiting
First Posted : June 27, 2012
Last Update Posted : June 27, 2012
Information provided by (Responsible Party):
China Medical University Hospital

Brief Summary:
In adult, the prevalence of mycobacterial infections is increased with age is largely unknown. IFN-gamma-IL-12/23 axis or NF-kappaB pathways might also plays crucial roles in adult against mycobacteria. Based on this hypothesis, the investigators had applied a functional assay to these pathways in patients with mycobacterial infection.

Condition or disease
Mycobacterium Infection

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Study Start Date : January 2011
Estimated Study Completion Date : December 2014

Resource links provided by the National Library of Medicine

Patients with mycobacterial infection

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Pateitns with Mycobacterium, Particular to the non Tuberculosis mycobacterium infection, in Taiwan

Inclusion Criteria:

  • Patients with mycobacterial infection

Exclusion Criteria:

  • Malignancy
  • Severe autoimmune
  • HIV infection

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01628744

Contact: Cheng-?Lung KU, Ph.D (886) (0)3 211-8800 ext 3496

Graduate Institute of Clinical Medical Science, China Medical University Recruiting
Taichung, Taiwan
Principal Investigator: Chih Y. Chi, M.D,         
Sponsors and Collaborators
China Medical University Hospital
Principal Investigator: Cheng-Lung KU, Ph.D Graduate Institute of clinical Medical Science, China Medical Univerity, Taiwan

Responsible Party: China Medical University Hospital Identifier: NCT01628744     History of Changes
Other Study ID Numbers: DMR-99-IRB-075-1
First Posted: June 27, 2012    Key Record Dates
Last Update Posted: June 27, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections