Evaluation and Comparison of Keloids and Second Degree Burns Blisters Fluid
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01627769|
Recruitment Status : Unknown
Verified February 2017 by Yaron Har-Shai, Carmel Medical Center.
Recruitment status was: Recruiting
First Posted : June 26, 2012
Last Update Posted : February 16, 2017
It is well documented that following thermal burns injury the development of hypertrophic scars and keloid (HSK) ranges between 40 to 90%. on the other hand It is well documented that cryosurgery wounds generally heal with minimal tissue contraction, resulting in good cosmetic results and with minimal complications.
The Aim of the study is To specify the burn and cryosurgery blister fluid for proteins, cytokines and cells and To compare between the above data regarding possible proteins, cytokines and cells, in regard to their possible effect on scarring and wound healing.
Also to Identify those components which are present only in the cryosurgery blister and which might have an anti-scarring effect and to characterize them biochemically.
|Condition or disease|
|Blisters Second Degree Burns Wounds|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||Comparison of the Blister Fluid Components of Second Degree Burned Patients With the Blister Fluid Components Following Intralesional Cryosurgery of Keloid Scars - A Feasibility Study.|
|Study Start Date :||July 2012|
|Estimated Primary Completion Date :||June 2018|
|Estimated Study Completion Date :||July 2018|
second degree blisters patients
blister fluids of second degree burns
blister fluids of cryosurgery wounds
- comparison of inflamation cells and proteins (proteomic evaluation) between blisters caused by heat and blisters caused by cryo injury [ Time Frame: at time of sampling. ]
the protein evaluation and comparison is achieved by the use of proteomic study which evaluate the quantity of about 700 different proteins in the fluid of the different blisters (heat blisters compared to "cryo" blisters).
we also evaluate the differences in quntities between the inflamation cells in each sample.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01627769
|Contact: yaron har-shai, Mdemail@example.com|
|Contact: nir gal or, Mdfirstname.lastname@example.org|
|Carmel Medical Center||Recruiting|
|Contact: yaron har-shai, Md 050-7866206 email@example.com|
|Contact: nir gal or, Md 054-5454636 firstname.lastname@example.org|
|Principal Investigator: yaron har-shai, Md|
|Principal Investigator:||yaron har-shai, Md||carmel medical center- ISRAEL|