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Prevalence of Pancreatic Cysts During Routine Endoscopic Ultra Sound

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Indiana University Identifier:
First received: June 18, 2012
Last updated: March 24, 2015
Last verified: March 2015
The investigators are interested in performing a detailed examination of the pancreas via EUS (Endoscopic Ultra Sound)for patients referred for a non-pancreatic condition. The hypothesis is to make a statistical determination of how many pancreatic cysts the investigators discover incidentally.

Condition Intervention
Pancreatic Cysts
Other: Diagnosis of a previously undetected pancreatic cyst

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Prevalence of Pancreatic Cysts During Routine EUS

Further study details as provided by Indiana University:

Primary Outcome Measures:
  • Prevalence of Pancreatic Cysts During Routine EUS [ Time Frame: 48 months ]
    Cross-sectional imaging identifies cystic neoplasms in up to 1.2% of the general population. However, data from an autopsy series reports pancreatic cysts in up to 24% of patients.EUS can identify small cysts that are not seen on CT scan, MRI or other cross sectional imaging we hypothesize that pancreatic cysts are present between 1.2 and 24% of the population, with rates varying by variables such as age and a previous diagnosis of pancreatitis. The purpose of this study is to identify the prevalence of pancreatic cysts in patients undergoing EUS for non-pancreatic indications .

  • The prevalence of pancreatic cysts incidentally found via EUS. [ Time Frame: 48 months ]

Estimated Enrollment: 400
Study Start Date: September 2009
Estimated Study Completion Date: January 2018
Estimated Primary Completion Date: January 2017 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Patients undergoing EUS
Patients undergoing EUS for non-pancreatic treatment.
Other: Diagnosis of a previously undetected pancreatic cyst
patients identified to have a pancreatic cyst, will need to be followed via imaging studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients were identified on the day of scheduled endoscopy.

Inclusion Criteria:

  • The inclusion criteria included: patients >18 years old with decision making capacity referred for EUS for any other indication other than the evaluation of a known pancreatic cyst, solid mass, or suspected mass.

Exclusion Criteria:

  • Any known history or evidence of the following from any previous imaging study: pancreatic cyst, solid mass, suspected pancreatic mass, dilated main pancreatic duct
  • Previous surgical resection of any portion of the upper GI tract such as Billroth II that would not permit complete EUS exam of the pancreas
  • Laboratory and/or clinical evidence of ongoing acute pancreatitis
  • Previous pancreatic surgical resection
  • Pregnancy
  • Incarceration
  • High risk for sedation
  • Coagulopathy and/or thrombocytopenia
  • The patients underwent a complete EUS examination of the pancreas.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01624363

United States, Indiana
University Hospital
Indianapolis, Indiana, United States, 46220-5121
Sponsors and Collaborators
Indiana University
Principal Investigator: John M. DeWitt, M.D. Indiana University
  More Information

Responsible Party: Indiana University Identifier: NCT01624363     History of Changes
Other Study ID Numbers: 0906-23
Study First Received: June 18, 2012
Last Updated: March 24, 2015

Keywords provided by Indiana University:
Pancreatic cysts incidentally found during EUS

Additional relevant MeSH terms:
Pancreatic Cyst
Pathological Conditions, Anatomical
Pancreatic Diseases
Digestive System Diseases processed this record on March 27, 2017