New Serological Markers for Eosinophilic Esophagitis
Recruitment status was: Recruiting
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Study Start Date:||January 2011|
patients with histopathological defined eosinophilic esophagitis
Guideline-based treatment with fluticasone 0,5 ml (1-0-1), step-up or step-down after 3 months based on the histopathological findings
The eosinophilic esophagitis (EE) is chronic inflammatory and immunological disease. The diagnosis of EE is based upon large numbers of eosinophils in the esophagus on histopathologic examination (> 20 eosinophils per high powered field in at least one specimen) despite acid suppression with a Proton-Pump-Inhibitor (PPI) for at least two weeks.
There are no diagnostic serological markers for EE so far, so that the purpose of the study is to investigate serological markers which are established in other allergic diseases.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01624129
|II. Medical Department, Technical University Munich|
|Munich, Bavaria, Germany, 81675|
|Principal Investigator:||Monther Bajbouj, MD||Technical University of Munich, 2nd Medical Department|