Plasma Adiponectin Level and Sleep Structures in Children With Prader-Willi Syndrome
Context: Adiponectin is an adipose tissue-derived hormone with an insulin sensitizing effect, and has been related to obstructive sleep apnea syndrome. In addition, children with Prader-Willi syndrome (PWS) suffer from excessive daytime sleepiness and the abnormality of rapid eye movement (REM) sleep.
Objective: To determine if the sleep stages are related to the plasma levels of adiponectin, resistin, and RBP4 (retinol binding protein-4), and whether these relationships are influenced by age, obesity and insulin resistance.
|Prader-Willi Syndrome Obesity|
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Plasma Adiponectin Level and Sleep Structures in Children With Prader-Willi Syndrome|
|Study Start Date:||January 2007|
|Study Completion Date:||June 2007|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01622751
|Principal Investigator:||Dong-Kyu Jin, M.D.||Samsung Medical Center, Sungkyunkwan University School of Medicine|