Motor Training for Fall Prevention
|ClinicalTrials.gov Identifier: NCT01621958|
Recruitment Status : Completed
First Posted : June 18, 2012
Last Update Posted : April 28, 2014
|Condition or disease||Intervention/treatment||Phase|
|Fall Prevention||Behavioral: Repeated perturbation training Behavioral: Minimal perturbation training||Not Applicable|
Slip-related falls often cause catastrophic injury for both frail and healthy older persons. Investigators have shown that, with motor training by repeated exposure to slips during walking, young adults are able to traverse a potential slipping hazard without losing their balance, regardless of whether a slip actually occurs or not. It is highly unlikely that these effects could be attributed to education or heightened awareness of the slipping threat alone. Furthermore, investigators have demonstrated that these improved motor skills acquired from a single session can be retained 4-6 months or longer upon re-testing, making such intervention highly attractive. Of greater interest, however, is the extent to which older adults can acquire and retain similar protective skills upon such training. This has not been tested to date. Also unknown is how potential confounding factors such as an older adult's functional status might interact with the training. These issues are of importance in that establishing a retainable preventive training regimen against slip-related falls would, without doubt, have major public health implications.
In this study, investigators will demonstrate that older adults can significantly reduce their near-term risk of backward balance loss and falls through motor training by repeated exposure to simulated slips interspersed with no-slip trials. Investigators will verify that awareness or observational learning alone cannot substitute for motor training through an awareness-control group. Investigators will then determine the extent to which adaptive improvements are retained over the course of a year. Finally, investigators will verify that although a single slip exposure may yield some retainable effect, this intensity control group will exhibit significantly less favorable long-term effect on the control of center of mass stability, body weight support, balance loss and fall upon slipping than the motor training group with repeated slips. In addition, investigator expect that the intensity-control group will also have a higher self-reported incidence of falls during the 12-month period than the motor training group with multiple slip exposure.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||212 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Motor Training for Fall Prevention: Adaptation and Retention in Older Adults|
|Study Start Date :||September 2008|
|Actual Primary Completion Date :||April 2012|
|Actual Study Completion Date :||April 2012|
|Experimental: Motor training||
Behavioral: Repeated perturbation training
One session consisting of 24 slips total interspersed with 16 nonslip trials (1 block of 8 slips, 3 non-slips, 2nd block of 8 slips, 3 non-slips, a mixed block consisting of 8 slips and 10 non-slips). Retest consisting of one slip exposure at either 6 months, 9 months or 12 months.
Other Name: Repeated slip training
|Placebo Comparator: Intensity control||
Behavioral: Minimal perturbation training
One session consisting of a single slip exposure. Retest consisting of one slip exposure at either 6 months, 9 months or 12 months.
Other Name: Single slip exposure
- Fall incidence [ Time Frame: 6 months ]
- Dynamic stability [ Time Frame: 6 months ]The dynamic stability will be evaluated based on the dynamic relationship of motion state (i.e., the combination of position and velocity) between the center of mass and the base of support. It will be calculated as the shortest distance from the instantaneous motion state of the center of mass to the threshold against backward fall. It is a dimensionless variable.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01621958
|United States, Illinois|
|Clinical Gait and Movement Analysis Laboratory|
|Chicago, Illinois, United States, 60612|
|Principal Investigator:||Yi-Chung Pai, PhD||University of Illinois at Chicago|