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The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01619917
Recruitment Status : Active, not recruiting
First Posted : June 14, 2012
Last Update Posted : November 3, 2020
Sponsor:
Information provided by (Responsible Party):
Dr. Sarvesh Logsetty, University of Manitoba

Brief Summary:

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our assessing the effects of fractional vascular lasers on burn scars. It has been hypothesized that the fractional vascular lasers work on mature scars to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. The retexturing/ resurfacing of the laser theoretically can decrease the visibility of the mesh pattern created by meshed split thickness skin graft).

Objective:

To determine the benefit of fractional vascular laser treatment in improving burn scar height, texture, vascularity and pliability in late burn scars.


Condition or disease Intervention/treatment Phase
Burn Scar Device: Fractional Vascular Laser Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 6 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars
Study Start Date : November 2012
Estimated Primary Completion Date : June 2022
Estimated Study Completion Date : June 2022

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Burns Scars

Arm Intervention/treatment
Active Comparator: Proximal
location of the scar proximal to heart
Device: Fractional Vascular Laser
laser energy will be applied to one of 2 sites (proximal or distal) depending on randomization result

Experimental: Distal
location of scar distal to heart
Device: Fractional Vascular Laser
laser energy will be applied to one of 2 sites (proximal or distal) depending on randomization result




Primary Outcome Measures :
  1. reduction in scar appearance [ Time Frame: every 3 weeks to 15 weeks ]
    examine with modified Vancouver Scar Scale



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • living in Winnipeg
  • burn scar 6-12 months old
  • Fitzpatrick skin type I-III
  • thermal burn scar on trunk or extremities

Exclusion Criteria:

  • open wound

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01619917


Locations
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Canada, Manitoba
University of Manitoba
Winnipeg, Manitoba, Canada, R3A 1R9
Sponsors and Collaborators
University of Manitoba
Investigators
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Principal Investigator: S Logsetty, MD University of Manitoba
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Responsible Party: Dr. Sarvesh Logsetty, Principal Investigator, University of Manitoba
ClinicalTrials.gov Identifier: NCT01619917    
Other Study ID Numbers: B2011: 075
First Posted: June 14, 2012    Key Record Dates
Last Update Posted: November 3, 2020
Last Verified: November 2020
Keywords provided by Dr. Sarvesh Logsetty, University of Manitoba:
burn
scar
laser
fractional
vascular
Additional relevant MeSH terms:
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Cicatrix
Burns
Wounds and Injuries
Fibrosis
Pathologic Processes