LEft Atrial Pacing in Diastolic Heart Failure (LEAD)
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ClinicalTrials.gov Identifier: NCT01618981
Verified January 2014 by Centre Hospitalier Universitaire Dijon. Recruitment status was: Recruiting
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Ages Eligible for Study:
65 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age ≥ 65
Sinus rhythm, PR < 220ms, QRS < 110ms
Heart failure (NYHA class III-IV or II with hospitalization for heart failure)
Ejection Fraction > 50%, restrictive mitral inflow, Lateral E/e' > 12 or septal E/e' > 15, Left atrial index volume > 34 ml/m²
Atrial dyssynchrony syndrome: (TTE) inter-atrial time delay ≥ 70ms (difference between tricuspid and mitral P-A intervals or between mitral and tricupsid P-A' intervals with DTI)
Left atrio-ventricular asynchrony: Time Difference between tricupsid and mitral A wave duration ≥ 35ms.