Glasgow Asthma and Allergy Study (GLAAS)
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|ClinicalTrials.gov Identifier: NCT01618318|
Recruitment Status : Completed
First Posted : June 13, 2012
Last Update Posted : December 5, 2013
In the past, doctors separated people with asthma into two groups, those with "allergic asthma" (about 2/3rds of people) and those with "non-allergic asthma". These labels are not much used now as the treatments for all people with asthma don't depend on this classification. However, new treatments for asthma may become available and the classification may again become important. It could be useful for clinicians to know how to identify which patients are likely to benefit from particular treatments.
Additionally, some new blood tests are becoming available and some of these might help to categorise the type of asthma people have. What the study hopes to do is to identify patient features which make a diagnosis of "allergic asthma" more likely and to see which new blood tests are most likely to be helpful in confirming this diagnosis.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||105 participants|
|Official Title:||Cross Sectional Study to Evaluate and Associate Clinical and Laboratory Features of People With Allergic and Non-allergic Asthma|
|Study Start Date :||June 2012|
|Actual Primary Completion Date :||October 2013|
|Actual Study Completion Date :||October 2013|
General asthma population
People with asthma, aged 18 years and over, non smoker, all severities of disease, regardless of treatment, broad inclusion and few exclusion criteria.
- Serum periostin level [ Time Frame: 1 day ]This is a cross sectional study. Participants will be assessed and tests conducted at a single visit
- skin prick test [ Time Frame: 1 day ]
- Serum total IgE [ Time Frame: 1 day ]
- Blood eosinophil count [ Time Frame: 1 day ]
- Blood neutrophil count [ Time Frame: 1 day ]
- Blood CD4 cells that are positive for CRTh2 [ Time Frame: 1 day ]
- Blood eosinophils expressing CRTh2 [ Time Frame: 1 day ]
- Spirometry [ Time Frame: 1 day ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01618318
|Dartford, Kent, United Kingdom, DA1 5GA|
|Principal Investigator:||John A Haughney, MB ChB||NSHI Ltd|