Study of Human Sensory Perception
|ClinicalTrials.gov Identifier: NCT01613911|
Recruitment Status : Completed
First Posted : June 7, 2012
Last Update Posted : December 8, 2014
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||6 participants|
|Official Title:||A Combined fMRI and Electrophysiological Study of Human Sensory Perception|
|Study Start Date :||March 2012|
|Actual Primary Completion Date :||November 2014|
|Actual Study Completion Date :||November 2014|
Epileptics having invasive monitoring
People between 10 and 65 years of age with epilepsy and who are coming in to have invasive electrophysiological monitoring.
- Reveal induced neuronal activity [ Time Frame: Approximately 3 hours over the course of 2-3 days during in-patient invasive electrophysiological monitoring. ]In the preprocessing stage, potential electrical interference will be removed from the raw signal using a linear-phase notch FIR filter. Each electrode will be de-referenced by subtraction of the averaged signal of all the electrodes, thus discarding non-neuronal contributions. Time-frequency decompositions will be calculated for each electrode based on Fourier transform amplitude spectrum in a 160ms sliding window with average step size of 6ms. This process is done per trial and averaged across trials in order to reveal induced neuronal activity, which is not time-locked to the stimuli.
- Calculate evoked response potentials. [ Time Frame: Approximately 3 hours over the course of 2-3 days during in-patient invasive electrophysiological monitoring. ]Evoked response potentials (ERPs) will be calculated by averaging the raw signal across the presentation of a specific stimulus for each patient, such as all samples of patients watching the movie clip.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01613911
|United States, Washington|
|Swedish Medical Center Epilepsy Center|
|Seattle, Washington, United States, 98122|