A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer
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|ClinicalTrials.gov Identifier: NCT01611584|
Recruitment Status : Withdrawn (PI left institution)
First Posted : June 5, 2012
Last Update Posted : November 13, 2014
|Condition or disease||Intervention/treatment||Phase|
|Lung Cancer in Normal and Malignant Tumors||Drug: ALA-induced Fluorescence||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||0 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer|
|Study Start Date :||June 2010|
|Actual Primary Completion Date :||July 2014|
|Actual Study Completion Date :||July 2014|
No arms for the trial. Participants will have proven or presumed lung cancer and will be assessed for participant by a research team member.
Drug: ALA-induced Fluorescence
ALA Dose- 20 mg/kg
- ALA-induced fluorescence- lung cancer [ Time Frame: Participants will be followed for duration of the hospital stay, and up to 3 weeks after ]Determine the relationship between ALA induced protoporphyrin IX (PplX) flourescence and histology in both normal and malignant tumors.
- Determine Feasibility of fluorescence [ Time Frame: Participants will be followed for the duration of their hospital study and up to 3 weeks after ]Determine feasibility of integrating fluorescence detection into surgical pratice of resection for lung cancer.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01611584
|United States, New Hampshire|
|Dartmouth-Hitchcock Medical Center|
|Lebanon, New Hampshire, United States, 03756|
|Principal Investigator:||Cherie P Erkmen, MD||Dartmouth-Hitchcock Medical Center|