Noninvasive Measurement of Cardiac Output in Pulmonary Hypertension Using Inert Gas Rebreathing
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Noninvasive Measurement of Cardiac Output in Pulmonary Hypertension Using Inert Gas Rebreathing|
- Cardiac output [ Time Frame: at baseline ] [ Designated as safety issue: No ]
|Study Start Date:||February 2012|
|Study Completion Date:||February 2014|
|Primary Completion Date:||February 2014 (Final data collection date for primary outcome measure)|
Inert Gas Rebreathing method enables non invasive measurement of cardiac output (CO) using the single rebreathing method. A mixture of blood soluble (N2O) and blood insoluble gas (SF6) and environmental air is inhaled and the amount of N2O, SF6, O2 and CO2 is measured by a photoacoustic analysator. The length of a measurement is about 1 minute.
As the gold standard measurement of CO is performed invasively, there is an urgent need for the development of non-invasive tools like IGR.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01606839
|Ludwig Boltzmann Institute for Lung Vascular Research|
|Principal Investigator:||Horst Olschewski, MD||Medical University of Graz|