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Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

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ClinicalTrials.gov Identifier: NCT01603992
Recruitment Status : Completed
First Posted : May 23, 2012
Last Update Posted : July 2, 2017
Information provided by:

Study Description
Brief Summary:


- Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment ( spontaneous quitting). Studies have suggested that there are some common strategies that many individuals use in spontaneous quitting, such as changing one s lifestyle or identity, reminding oneself of negative consequences, support from family and friends, and religion. However, more research is needed to determine potential treatment strategies for marijuana use.


  • To identify strategies used to help with marijuana quitting among non-treatment seeking adult marijuana users.
  • To identify withdrawal symptoms experienced during marijuana quitting and their relationship to the quitting strategies used and the outcome of the quit attempt.
  • To evaluate whether subgroups of marijuana users differ in their experience of marijuana quitting.


- Individuals at least 18 years of age who have made at least one attempt to quit marijuana use.


  • The study will consist of one visit of approximately 1 to 2 hours.
  • Participants will fill out three questionnaires. The questionnaires have different types of questions, and will ask about background and lifestyle, marijuana use and craving patterns and behaviors, and difficulties in previous attempts to quit using marijuana.

Condition or disease
Cannabis Abuse Cannabis Dependence

Detailed Description:
Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment (so-called spontaneous quitting). This study will use two self-report questionnaires to collect information on the socio-demographic characteristics, marijuana use history, most difficult marijuana quit experience, and marijuana craving from a convenience sample of 1230 adult, non-treatment-seeking marijuana users. The questionnaires take 45-60 minutes to administer. Data will be analyzed for patterns and correlations among the characteristics of the quit attempt, including any withdrawal symptoms, quitting strategies used, and its success. The marijuana craving data will be analyzed to evaluate the validity of this measure of marijuana craving. There are no direct benefits to subjects from study participation. The scientific benefit is an improved understanding of spontaneous quitting of marijuana use, which may lead to improved interventions for marijuana users in the future. There are no physical risks to subjects. There are risks of anxiety or embarrassment while taking the questionnaire and of loss of confidentiality of sensitive information collected about subjects.

Study Design

Study Type : Observational
Estimated Enrollment : 1230 participants
Official Title: Quitting Marijuana Use: Self-Report Study of Quitting Strategies and Withdrawal Symptoms
Study Start Date : November 8, 2005
Estimated Study Completion Date : May 3, 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Marijuana
U.S. FDA Resources

Groups and Cohorts

Outcome Measures

Primary Outcome Measures :
  1. Marijuana Quit Questionnaire [ Time Frame: 1 to 2 hours ]

Secondary Outcome Measures :
  1. Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

    1. age 18 or older
    2. have made at least one attempt to quit marijuana use
    3. able to give valid informed consent
    4. ability to understand English
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01603992

United States, Maryland
National Institute on Drug Abuse, Biomedical Research Center (BRC)
Baltimore, Maryland, United States, 21224
Maryland Psychiatric Research Center (MPRC) 55 Wade Avenue
Catonsville, Maryland, United States, 21228
United States, South Carolina
Medical University of S. Carolina
Charleston, South Carolina, United States, 29425
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Principal Investigator: David A Gorelick, M.D. National Institute on Drug Abuse (NIDA)
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT01603992     History of Changes
Obsolete Identifiers: NCT00679016
Other Study ID Numbers: 999906408
First Posted: May 23, 2012    Key Record Dates
Last Update Posted: July 2, 2017
Last Verified: May 3, 2012

Keywords provided by National Institutes of Health Clinical Center (CC):
Drug Use

Additional relevant MeSH terms:
Marijuana Abuse
Substance Withdrawal Syndrome
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders