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Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms

This study has been completed.
Information provided by:
National Institutes of Health Clinical Center (CC) Identifier:
First received: May 19, 2012
Last updated: April 19, 2017
Last verified: May 3, 2012


- Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment ( spontaneous quitting). Studies have suggested that there are some common strategies that many individuals use in spontaneous quitting, such as changing one s lifestyle or identity, reminding oneself of negative consequences, support from family and friends, and religion. However, more research is needed to determine potential treatment strategies for marijuana use.


  • To identify strategies used to help with marijuana quitting among non-treatment seeking adult marijuana users.
  • To identify withdrawal symptoms experienced during marijuana quitting and their relationship to the quitting strategies used and the outcome of the quit attempt.
  • To evaluate whether subgroups of marijuana users differ in their experience of marijuana quitting.


- Individuals at least 18 years of age who have made at least one attempt to quit marijuana use.


  • The study will consist of one visit of approximately 1 to 2 hours.
  • Participants will fill out three questionnaires. The questionnaires have different types of questions, and will ask about background and lifestyle, marijuana use and craving patterns and behaviors, and difficulties in previous attempts to quit using marijuana.

Cannabis Abuse
Cannabis Dependence

Study Type: Observational
Official Title: Quitting Marijuana Use: Self-Report Study of Quitting Strategies and Withdrawal Symptoms

Resource links provided by NLM:

Further study details as provided by National Institutes of Health Clinical Center (CC):

Primary Outcome Measures:
  • Marijuana Quit Questionnaire [ Time Frame: 1 to 2 hours ]

Secondary Outcome Measures:
  • Marijuana Craving Questionnaire, and Additional Questions about Marijuana Craving

Estimated Enrollment: 1230
Study Start Date: November 8, 2005
Estimated Study Completion Date: May 3, 2012
Detailed Description:
Marijuana is the most widely used illicit drug in the world, yet relatively little is known about users who try to quit without formal treatment (so-called spontaneous quitting). This study will use two self-report questionnaires to collect information on the socio-demographic characteristics, marijuana use history, most difficult marijuana quit experience, and marijuana craving from a convenience sample of 1230 adult, non-treatment-seeking marijuana users. The questionnaires take 45-60 minutes to administer. Data will be analyzed for patterns and correlations among the characteristics of the quit attempt, including any withdrawal symptoms, quitting strategies used, and its success. The marijuana craving data will be analyzed to evaluate the validity of this measure of marijuana craving. There are no direct benefits to subjects from study participation. The scientific benefit is an improved understanding of spontaneous quitting of marijuana use, which may lead to improved interventions for marijuana users in the future. There are no physical risks to subjects. There are risks of anxiety or embarrassment while taking the questionnaire and of loss of confidentiality of sensitive information collected about subjects.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

    1. age 18 or older
    2. have made at least one attempt to quit marijuana use
    3. able to give valid informed consent
    4. ability to understand English
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01603992

United States, Maryland
National Institute on Drug Abuse, Biomedical Research Center (BRC)
Baltimore, Maryland, United States, 21224
Maryland Psychiatric Research Center (MPRC) 55 Wade Avenue
Catonsville, Maryland, United States, 21228
United States, South Carolina
Medical University of S. Carolina
Charleston, South Carolina, United States, 29425
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Principal Investigator: David A Gorelick, M.D. National Institute on Drug Abuse (NIDA)
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT01603992     History of Changes
Obsolete Identifiers: NCT00679016
Other Study ID Numbers: 999906408
Study First Received: May 19, 2012
Last Updated: April 19, 2017

Keywords provided by National Institutes of Health Clinical Center (CC):
Drug Use

Additional relevant MeSH terms:
Marijuana Abuse
Substance Withdrawal Syndrome
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders processed this record on May 25, 2017