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Angiographie and OCT in Macula and Retinal Diseases

This study has been completed.
Information provided by (Responsible Party):
Stefan Sacu, Medical University of Vienna Identifier:
First received: May 19, 2012
Last updated: May 21, 2012
Last verified: May 2012
The purpose of this study is to investigate the morphological and angiological retinal changes in different macular diseases.

Macular Edema

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Stefan Sacu, Medical University of Vienna:

Enrollment: 30
Study Start Date: August 2008
Study Completion Date: September 2011
Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Healthy volunteers
St.p. Pars plana vitrectomy

Detailed Description:
Recently, a new generation of OCT devices relying on spectral domain technology (SD-OCT) has been introduced and allows for higher-resolution imaging. Based on this technology we can identify variable changes at the retinal surface such as, retinal thickening with cyst formation, swelling in the inner and outer nuclear layers and subretinal fluid. The introduction of an eye-tracking mode has allowed a better insight into the development of retinal morphologic changes The aim of this study was to investigate the incidence and structural morphology of PCME after successful uncomplicated cataract surgery in patients with previous pars plana vitrectomy (PPV) and indocyanine green-assisted peeling of an epiretinal membrane and the internal limiting membrane (ILM).

Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Twenty eyes of 20 patients with previous 23-gauge PPV and ILM peeling (PPV group) and 15 consecutive eyes with senile cataract with a healthy macula (control group) were included.

Inclusion Criteria:

  • previous 23-gauge PPV and ILM peeling

Exclusion Criteria:

  • history of branch retinal vein occlusion
  • central retinal vein occlusion
  • wet macular degeneration
  • diabetic retinopathy
  • uveitis or other inflammatory eye disease.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01603823

Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Stefan Sacu, Assoc.Prof., Medical University of Vienna Identifier: NCT01603823     History of Changes
Other Study ID Numbers: 10082007
Study First Received: May 19, 2012
Last Updated: May 21, 2012

Keywords provided by Stefan Sacu, Medical University of Vienna:
macular edema

Additional relevant MeSH terms:
Macular Edema
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases processed this record on June 22, 2017