Angiographie and OCT in Macula and Retinal Diseases

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01603823
Recruitment Status : Completed
First Posted : May 22, 2012
Last Update Posted : May 22, 2012
Information provided by (Responsible Party):
Stefan Sacu, Medical University of Vienna

Brief Summary:
The purpose of this study is to investigate the morphological and angiological retinal changes in different macular diseases.

Condition or disease
Macular Edema

Detailed Description:
Recently, a new generation of OCT devices relying on spectral domain technology (SD-OCT) has been introduced and allows for higher-resolution imaging. Based on this technology we can identify variable changes at the retinal surface such as, retinal thickening with cyst formation, swelling in the inner and outer nuclear layers and subretinal fluid. The introduction of an eye-tracking mode has allowed a better insight into the development of retinal morphologic changes The aim of this study was to investigate the incidence and structural morphology of PCME after successful uncomplicated cataract surgery in patients with previous pars plana vitrectomy (PPV) and indocyanine green-assisted peeling of an epiretinal membrane and the internal limiting membrane (ILM).

Study Type : Observational
Actual Enrollment : 30 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : August 2008
Actual Primary Completion Date : February 2010
Actual Study Completion Date : September 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Edema

Healthy volunteers
St.p. Pars plana vitrectomy

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Twenty eyes of 20 patients with previous 23-gauge PPV and ILM peeling (PPV group) and 15 consecutive eyes with senile cataract with a healthy macula (control group) were included.

Inclusion Criteria:

  • previous 23-gauge PPV and ILM peeling

Exclusion Criteria:

  • history of branch retinal vein occlusion
  • central retinal vein occlusion
  • wet macular degeneration
  • diabetic retinopathy
  • uveitis or other inflammatory eye disease.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01603823

Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Stefan Sacu, Assoc.Prof., Medical University of Vienna Identifier: NCT01603823     History of Changes
Other Study ID Numbers: 10082007
First Posted: May 22, 2012    Key Record Dates
Last Update Posted: May 22, 2012
Last Verified: May 2012

Keywords provided by Stefan Sacu, Medical University of Vienna:
macular edema

Additional relevant MeSH terms:
Macular Edema
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases