Effect of Zinc Supplementation on Serum Zinc Level in Nursing Home Elderly
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|ClinicalTrials.gov Identifier: NCT01599572|
Recruitment Status : Completed
First Posted : May 16, 2012
Last Update Posted : May 21, 2015
Background: Zinc supplementation has the potential to improve serum zinc levels and immunity of zinc deficient nursing home elderly.
Objective: To determine the effect of zinc supplementation of 30mg/d for 3 months on serum zinc levels and T-cell mediated function of zinc deficient nursing home elderly.
Design: This is a randomized, double-blind, placebo-controlled study. Outcome measures included change in serum zinc levels and various T-cell mediated immune factors between baseline and month 3.
Hypotheses: The investigators hypothesize that zinc supplementation of 30mg/d for 3 months will improve serum zinc levels as well as various T-cell mediated immune factors in zinc deficient nursing home elderly.
|Condition or disease||Intervention/treatment||Phase|
|Disorder of Immune Function||Other: zinc supplementation||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||31 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Zinc Intervention in Nursing Home Elderly|
|Study Start Date :||July 2009|
|Actual Primary Completion Date :||January 2011|
|Actual Study Completion Date :||January 2011|
Experimental: 30mg/day zinc supplementation
30mg/day of zinc supplement provided for 3 months to zinc deficient elderly
Other: zinc supplementation
30mg/day of zinc in the form of zinc gluconate
Other Name: zinc was provided in the form of zinc gluconate
- serum zinc concentration [ Time Frame: 3 months ]
- lymphocyte proliferation [ Time Frame: 3 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01599572
|Principal Investigator:||Simin N Meydani, DVM, PhD||HNRCA-tufts University|