Effect of Zinc Supplementation on Serum Zinc Level in Nursing Home Elderly
|ClinicalTrials.gov Identifier: NCT01599572|
Recruitment Status : Completed
First Posted : May 16, 2012
Last Update Posted : May 21, 2015
Background: Zinc supplementation has the potential to improve serum zinc levels and immunity of zinc deficient nursing home elderly.
Objective: To determine the effect of zinc supplementation of 30mg/d for 3 months on serum zinc levels and T-cell mediated function of zinc deficient nursing home elderly.
Design: This is a randomized, double-blind, placebo-controlled study. Outcome measures included change in serum zinc levels and various T-cell mediated immune factors between baseline and month 3.
Hypotheses: The investigators hypothesize that zinc supplementation of 30mg/d for 3 months will improve serum zinc levels as well as various T-cell mediated immune factors in zinc deficient nursing home elderly.
|Condition or disease||Intervention/treatment||Phase|
|Disorder of Immune Function||Other: zinc supplementation||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||31 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Zinc Intervention in Nursing Home Elderly|
|Study Start Date :||July 2009|
|Primary Completion Date :||January 2011|
|Study Completion Date :||January 2011|
Experimental: 30mg/day zinc supplementation
30mg/day of zinc supplement provided for 3 months to zinc deficient elderly
Other: zinc supplementation
30mg/day of zinc in the form of zinc gluconate
Other Name: zinc was provided in the form of zinc gluconate
- serum zinc concentration [ Time Frame: 3 months ]
- lymphocyte proliferation [ Time Frame: 3 months ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01599572
|Principal Investigator:||Simin N Meydani, DVM, PhD||HNRCA-tufts University|