Resistance Exercise in Rheumatic Disease
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01599260|
Recruitment Status : Recruiting
First Posted : May 15, 2012
Last Update Posted : August 18, 2017
|Condition or disease||Intervention/treatment|
|Rheumatoid Arthritis Systemic Vasculitis||Other: Resistance Exercise|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Resistance Exercise in Rheumatic Disease|
|Actual Study Start Date :||May 2012|
|Estimated Primary Completion Date :||July 2018|
|Estimated Study Completion Date :||July 2018|
Experimental: Resistance Exercise
Subjects will participate in a 16 week long resistance exercise program which will consist of 2 30-minute individually supervised sessions per week.
Other: Resistance Exercise
Two 30-minute individually supervised exercise sessions per week for 16-weeks
- Safety [ Time Frame: 16 weeks ]To ensure safety and tolerance of a resistance exercise protocol for patients with systemic vasculitis or rheumatoid arthritis. We will measure disease activity before and after each exercise session to determine if there is an association with the exercise program. We will track any major (and minor) injuries which are attributed to the exercise program.
- Change in Body composition after 16 weeks of resistance exercise [ Time Frame: 16 weeks ]To assess change in body composition associated with this resistance exercise protocol (after 16 weeks).
- Change in Strength after 16 weeks of resistance exercise [ Time Frame: 16 weeks ]We will test if strength increases before and after the exercise intervention
- Change in Functional status after 16 weeks of resistance exercise [ Time Frame: 16 weeks ]We will determine if functional status, as measured by the short physical performance battery, improves after 16 weeks
- Change in inflammatory cytokines (CRP, ESR, IL6) after 16 weeks of resistance exercise [ Time Frame: 16 weeks ]Participants will have blood drawn before and after 16 weeks of exercise to determine if changes have occurred in their inflammatory cytokines.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01599260
|Contact: Rebecca Manno, MDemail@example.com|
|Contact: Marilyn C Towns, BScfirstname.lastname@example.org|
|United States, Maryland|
|Johns Hopkins Bayview Medical Campus||Recruiting|
|Baltimore, Maryland, United States, 21224|
|Contact: Rebecca Manno, MD 410-550-0722|
|Principal Investigator:||Rebecca L Manno, M.D.||Johns Hopkins University|