Detecting Respiratory Viruses in Upper and Lower Respiratory Tract Samples
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|ClinicalTrials.gov Identifier: NCT01597089|
Recruitment Status : Terminated
First Posted : May 11, 2012
Last Update Posted : May 3, 2018
- Bronchoalveolar lavage (BAL) is a procedure where a tube is passed through the mouth or nose into the lungs. Fluid is squirted through the tube into a part of the lung and then collected for examination. It is used to detect respiratory viruses. BAL is a relatively invasive procedure, and researchers want to test the accuracy of other procedures that do not involve collecting fluid from the lungs. The nasopharynx is the area of the upper throat that lies behind the nose. Researchers want to see if a swab taken from this area is as accurate as a BAL sample.
- To see if a nasopharynx swab can be used to detect respiratory viruses as well as BAL samples.
- Individuals at least 12 years of age who will have a bronchoscopy to collect a BAL sample to test for respiratory viruses.
- Participants will be screened with a physical exam and medical history.
- Participants will have a BAL sample collected.
- Participants will then have a nasopharynx swab. The swab will be inserted into the nose, left in place for up to 10 seconds, and then removed
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||35 participants|
|Official Title:||Detection of Respiratory Viruses in Upper and Lower Respiratory Tract Specimens Using a Rapid Multiplex PCR|
|Study Start Date :||September 1, 2012|
|Study Completion Date :||May 1, 2018|
- The presence or absence of one or more of the 15 respiratory viruses in upper or lower respiratory tract samples using the FilmArray assay. [ Time Frame: Within 30 days after collection ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01597089
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Principal Investigator:||Daniel S Chertow, M.D.||National Institutes of Health Clinical Center (CC)|