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Oxytocin, Couple Interaction and Wound Healing

This study has been completed.
Swiss National Science Foundation
Information provided by (Responsible Party):
University of Zurich Identifier:
First received: May 7, 2012
Last updated: February 24, 2014
Last verified: February 2014

effects of intranasal oxytocin and couple interaction on wound healing.

  • Trial with medicinal product

Condition Intervention Phase
Healthy Volunteers Drug: Syntocinon (Oxytocin) nasal spray Drug: Placebo Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Investigator)
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by University of Zurich:

Primary Outcome Measures:
  • wound size [ Time Frame: seven days ]
    wound healing process within seven days after wounding

Enrollment: 160
Study Start Date: October 2011
Study Completion Date: October 2013
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: nasal spray Drug: Syntocinon (Oxytocin) nasal spray
two-times daily self-administration of nasal spray containing active substance (oxytocin) during five days after wounding.
Placebo Comparator: Placebo Drug: Placebo
two-times daily self-administration of nasal spray containing placebo during five days after wounding.


Ages Eligible for Study:   21 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria:

  • healthy heterosexual couples
  • in a stable relationship since > 1 year

Exclusion criteria: pregnancy

  • breast feeding
  • heavy smoking (> 5 cigarettes/d)
  • extensive skin disease
  • artificial UV irradiation during < 3 months before study inclusion
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01594775

University Hospital Zurich, Dept. of Dermatology
Zurich, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Swiss National Science Foundation
Study Director: 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich
Principal Investigator: Severin Laeuchli, MD University Hospital Zurich, Division of Dermatology
  More Information

Responsible Party: University of Zurich Identifier: NCT01594775     History of Changes
Other Study ID Numbers: KEK-ZH-NR: 2009-0063
Study First Received: May 7, 2012
Last Updated: February 24, 2014

Additional relevant MeSH terms:
Reproductive Control Agents
Physiological Effects of Drugs processed this record on July 28, 2017