Influence of Transcranial Direct Current Stimulation on Cortical Plasticity in Concussed Athletes
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|ClinicalTrials.gov Identifier: NCT01593956|
Recruitment Status : Unknown
Verified May 2013 by Jonathan List, Charite University, Berlin, Germany.
Recruitment status was: Recruiting
First Posted : May 8, 2012
Last Update Posted : May 23, 2013
Concussed athlethes have discrete decreased abilities in motor learning. Recent research could further show, that cortical plasticity, as measured by transcranial magnetic stimulation (TMS) is reduced. This is possibly due to an increased GABAergic activity, what have been found in concussed athletes by paired pulse protocols in TMS.
GABAergic acitivty can be modulated by transcranial direct current stimulation (tDCS) in a polar-specific manner: anodal tDCS was able to decrease GABA, whereas cathodal tDCS increased tDCS.
Our study aimes to assess the influence of anodal tDCS on cortical plsticity in concussed athlethes. We hypothesize, that anodal tDCS is able to increase cortical plsticity in concussed athlethes.
|Condition or disease||Intervention/treatment||Phase|
|Concussed Athletes Healthy Controls||Behavioral: tDCS||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Official Title:||Influence of Anodal Transcranial Direct Current Stimulation on Cortical Plasticity in Concussed Athletes and Healthy Volunteers|
|Study Start Date :||March 2012|
|Estimated Primary Completion Date :||July 2013|
|Concussed athletes||Behavioral: tDCS|
|Healthy controls||Behavioral: tDCS|
- Improvement of cortical plasticity after anodal tDCS in concussed athletes
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01593956
|Charité - Department of neurology||Recruiting|
|Berlin, Germany, 10117|
|Contact: Jonathan List, MD +40 30 450560223 Jonathan.List@charite.de|
|Contact: Agnes Flöel, Prof. +40 30 450660284 email@example.com|
|Principal Investigator: Jonathan List, MD|
|Principal Investigator: Agnes Flöel, Prof|
|Principal Investigator:||Jonathan List, MD||Charité - Department of Neurology|
|Principal Investigator:||Agnes Flöel, Prof.||Charité - Department of Neurology|