Hereditary Haemorrhagic Telangiectasia Flight Safety Study (Flying and HHT)
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|ClinicalTrials.gov Identifier: NCT01590121|
Recruitment Status : Completed
First Posted : May 2, 2012
Last Update Posted : May 29, 2015
Hereditary Haemorrhagic Telangiectasia (HHT) is a condition in which sufferers have abnormal blood vessels which makes them more likely to bleed than other people, particularly in the lungs, which results in low blood oxygen levels. Flying may make this worse and cause problems. The investigators want to know if there are an increased number of problems on flights compared to on land.
The investigators currently do not have any evidence based guidelines on air travel to best advice people who suffer with HHT. The investigators would therefore like to ask individuals who have HHT about their experience on a flight, using a postal questionnaire.
|Condition or disease||Intervention/treatment|
|Hereditary Haemorrhagic Telangiectasia||Other: Aeroplane flight in the past- no active intervention for study Other: Questionnaire|
Individuals with Hereditary Haemorrhagic Telangiectasia (HHT) previously reviewed at HHTIC London will be sent an invitation to participate in a short questionnaire study.
Quantitative variables from the questionnaires for statistical analysis will be the number of individuals responding (and number of questionnaires sent out); number of flights taken and number of complications, subgrouped by type, and flight duration in hours. Complication rates will be expressed as proportion of person flight hours.
The quantitative data from the questionnaire will then be compared with quantitative data from patients' medical records using non parametric methods such as Mann Whitney for univariate analyses.
|Study Type :||Observational|
|Actual Enrollment :||145 participants|
|Official Title:||A Questionnaire Based Study to Evaluate the Safety of Flying in Hereditary Haemorrhagic Telangiectasia (HHT)|
|Study Start Date :||January 2010|
|Primary Completion Date :||October 2011|
|Study Completion Date :||October 2011|
|Pateints with hereditary haemorrhagic telangiectasia||
Other: Aeroplane flight in the past- no active intervention for study
Aeroplane flight(s) previously taken by study participantsOther: Questionnaire
Flight by aeroplane (previous)
- Self reported medical complication [ Time Frame: During or in 6 weeks post flight ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01590121
|HammersmithHospital, Imperial College Healthcare NHS Trust|
|London, United Kingdom, W12 0NN|
|Principal Investigator:||Claire L Shovlin, PhD MA MB BChir FRCP||Imperial College London|