Studying Gene Expression and Location in Samples From Patients With Brain Tumors
|ClinicalTrials.gov Identifier: NCT01585389|
Recruitment Status : Completed
First Posted : April 25, 2012
Last Update Posted : May 18, 2016
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to brain tumors.
PURPOSE: This research studies gene expression and location in samples from patients with brain tumors.
|Condition or disease||Intervention/treatment|
|Brain and Central Nervous System Tumors||Genetic: gene expression analysis Genetic: genetic linkage analysis Genetic: microarray analysis Other: immunohistochemistry staining method Other: laboratory biomarker analysis|
- To determine the expression and subcellular localization of nei endonuclease VIII-like 3 (NEIL3) in brain tumors.
OUTLINE: Tissue microarray samples are analyzed for NEIL3 expression and subcellular localization by immunohistochemical methods.
|Study Type :||Observational|
|Estimated Enrollment :||10 participants|
|Official Title:||Expression and Subcellular Localization of NEIL3 in Tumors|
|Study Start Date :||April 2012|
|Primary Completion Date :||May 2016|
- Correlation of NEIL3 expression and/or nuclear localization with tumor type or grade with respect to degree of differentiation
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01585389
|Principal Investigator:||Heithem M. El-Hodiri, PhD||Nationwide Children's Hospital|