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Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar

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ClinicalTrials.gov Identifier: NCT01583491
Recruitment Status : Unknown
Verified April 2012 by Majid Eshghpour, Mashhad University of Medical Sciences.
Recruitment status was:  Active, not recruiting
First Posted : April 24, 2012
Last Update Posted : April 25, 2012
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.

Condition or disease Intervention/treatment Phase
Mastication Disorder Procedure: autologous platlet rich fibrin Procedure: one side in control group Phase 4

Detailed Description:
After extraction or surgical removal of third molar, a deep bony pocket created behind the second molar specially in the mandible. For reduction of this problem, investigators, needed to acceleration tissue healing. For this purpose, investigators used platelet rich fibrin (autologous) and followed patient for 3 months.

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Evaluation of Platelet Rich Fibrin Efficacy on Reduction of Periodontal Problems
Study Start Date : December 2011
Estimated Primary Completion Date : April 2012
Estimated Study Completion Date : May 2012
Arms and Interventions

Arm Intervention/treatment
Active Comparator: prf group.peridontal problem
prf insert into surgical site immediate after surgery
Procedure: autologous platlet rich fibrin
one dose immediate after surgery
Other Name: prf
Placebo Comparator: control group Procedure: one side in control group
control group insert any things after surgery


Outcome Measures

Primary Outcome Measures :
  1. Measurement of periodontal pocket depth at mid buccal, disto buccal and distolingual of mandibular second molar [ Time Frame: 4 months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • have 2 impacted third molars

Exclusion Criteria:

  • periodontal disease
  • history of periodontal surgery
More Information

Responsible Party: Majid Eshghpour, assistant professor, Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01583491     History of Changes
Other Study ID Numbers: 900093
First Posted: April 24, 2012    Key Record Dates
Last Update Posted: April 25, 2012
Last Verified: April 2012

Keywords provided by Majid Eshghpour, Mashhad University of Medical Sciences:
platelet rich fibrin
mandibular third molar
periodontal problem