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Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2012 by Majid Eshghpour, Mashhad University of Medical Sciences.
Recruitment status was:  Active, not recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01583491
First Posted: April 24, 2012
Last Update Posted: April 25, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Majid Eshghpour, Mashhad University of Medical Sciences
  Purpose
The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.

Condition Intervention Phase
Mastication Disorder Procedure: autologous platlet rich fibrin Procedure: one side in control group Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Evaluation of Platelet Rich Fibrin Efficacy on Reduction of Periodontal Problems

Further study details as provided by Majid Eshghpour, Mashhad University of Medical Sciences:

Primary Outcome Measures:
  • Measurement of periodontal pocket depth at mid buccal, disto buccal and distolingual of mandibular second molar [ Time Frame: 4 months ]

Enrollment: 30
Study Start Date: December 2011
Estimated Study Completion Date: May 2012
Estimated Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: prf group.peridontal problem
prf insert into surgical site immediate after surgery
Procedure: autologous platlet rich fibrin
one dose immediate after surgery
Other Name: prf
Placebo Comparator: control group Procedure: one side in control group
control group insert any things after surgery

Detailed Description:
After extraction or surgical removal of third molar, a deep bony pocket created behind the second molar specially in the mandible. For reduction of this problem, investigators, needed to acceleration tissue healing. For this purpose, investigators used platelet rich fibrin (autologous) and followed patient for 3 months.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • have 2 impacted third molars

Exclusion Criteria:

  • periodontal disease
  • history of periodontal surgery
  Contacts and Locations
No Contacts or Locations Provided
  More Information

Responsible Party: Majid Eshghpour, assistant professor, Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01583491     History of Changes
Other Study ID Numbers: 900093
First Submitted: December 7, 2011
First Posted: April 24, 2012
Last Update Posted: April 25, 2012
Last Verified: April 2012

Keywords provided by Majid Eshghpour, Mashhad University of Medical Sciences:
platelet rich fibrin
mandibular third molar
periodontal problem