Serum DCAMKL1 Pre and Post Treatment in Patients With Pancreatic Cancer

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
University of Oklahoma Identifier:
First received: April 17, 2012
Last updated: December 2, 2014
Last verified: December 2014
The investigators believe DCAMKL-1 is a stem cell tumor marker and is elevated in patients with pancreatic cancer. The investigators would like to analyze its expression pre and post treatment, to gauge the correlation between current pancreatic cancer therapies and the expression of DCAMKL-1

Pancreatic Cancer

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Expression Patterns of Stem Cell Marker Doublecortin and CaM Kinase-Like-1 (DCAMKL-1) in Human Pancreatic Adenocarcinoma

Resource links provided by NLM:

Further study details as provided by University of Oklahoma:

Estimated Enrollment: 60
Study Start Date: October 2010
Estimated Study Completion Date: July 2015
Estimated Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)
Surgery group
Patients with pancreatic cancer who undergo surgical treatment only
Chemotherapy group
Patients with pancreatic cancer who undergo chemotherapy treatment only
Neoadjuvant group
Patients with pancreatic cancer who undergo neoadjuvant chemotherapy and surgery
Adjuvant group
Patients with pancreatic cancer who undergo surgery followed by chemotherapy


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Human patients with pancreatic cancer undergo various treatments for pancreatic cancer. We will examine the expression of Dcamkl-1 pre and post therapy (including, chemotherapy only, surgery only, neoadjuvant and adjuvant therapies) to correlate treatment with a change in DCAMKl-1 expression.

Inclusion Criteria:

  • pancreatic cancer

Exclusion Criteria:

  • age < 18, history of other types of cancer
  Contacts and Locations
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Please refer to this study by its identifier: NCT01580241

United States, Oklahoma
Stephensen Cancer Center
Oklahoma City, Oklahoma, United States, 73104
Sponsors and Collaborators
University of Oklahoma
Principal Investigator: Courtney Houchen, MD University of Oklahoma
  More Information

No publications provided

Responsible Party: University of Oklahoma Identifier: NCT01580241     History of Changes
Other Study ID Numbers: 2606
Study First Received: April 17, 2012
Last Updated: December 2, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Pancreatic Neoplasms
Digestive System Diseases
Digestive System Neoplasms
Endocrine Gland Neoplasms
Endocrine System Diseases
Neoplasms by Site
Pancreatic Diseases processed this record on November 25, 2015