Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression
|ClinicalTrials.gov Identifier: NCT01579942|
Recruitment Status : Terminated (The study was ultimately not funded by the sponsor. No subjects were enrolled.)
First Posted : April 18, 2012
Last Update Posted : March 6, 2017
|Condition or disease|
|Major Depressive Disorder|
|Study Type :||Observational|
|Estimated Enrollment :||70 participants|
|Official Title:||Potential Use Of Brain Network Activation Analysis Using Evoked Response Potentials to Diagnose Major Depression and Assess Response to Antidepressant Treatment|
|Study Start Date :||April 2012|
Patients with Major Depressive Disorder
Patients who have Major Depressive Disorder and are taking a Selective Serotonin Re-uptake Inhibitor (SSRI) as part of another study at our clinic.
Patient with no history of significant mental health problems.
- Brain Network Analysis group patterns [ Time Frame: 8 weeks ]The investogators will make a comparison of Functional networks of brain activity (BNA™) in subjects with MDD and healthy individuals measured using analysis of EEG Event Related Potential (ERP) data [ Time Frame: Baseline, 1 week after the first dose of antidepressant treatment, end of the treatment phase].
- Identify possible predictors of treatment response [ Time Frame: 8 weeks ]
The investigators will examine the agreement between clinical diagnoses and the change of Brain Network Activation (BNA™)Scores in MDD subjects and healthy controls.
Subjects will undergo clinical diagnostic interviews and a comprehensive neuropsychological and cognitive assessment, and then complete 1 EEG scan of approximately 1 hour. The results of the BNA will be compared to the results of the clinical diagnostic interviews and tests.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01579942
|United States, Massachusetts|
|Depression Clinical and Research Program|
|Boston, Massachusetts, United States, 02114|
|Principal Investigator:||Cristina Cusin, MD||Massachusetts General Hospital|
|Principal Investigator:||Ottavio Vitolo, MD||Massachusetts General Hospital|