Effect of Stellate Ganglion Block on Meniere's Disease
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01574313 |
Recruitment Status
:
Completed
First Posted
: April 10, 2012
Last Update Posted
: April 11, 2012
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Vertigo Meniere Disease | Procedure: stellate ganglion block Drug: 0.25mg, fludiazine Drug: 25mg cephadol@ (diphenidol) Drug: 200mg kentons@ (tocopherol nicotinate). | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 20 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Effect of Stellate Ganglion Block on Meniere's Disease |
Study Start Date : | April 2010 |
Actual Primary Completion Date : | April 2011 |
Actual Study Completion Date : | March 2012 |

Arm | Intervention/treatment |
---|---|
Experimental: Stellate ganglion block
treated with SGB
|
Procedure: stellate ganglion block
stellate ganglion block
|
Active Comparator: Oral medication
treated with oral medications: 0.25mg of erispan@ (fludiazine) , 25mg cephadol@ (diphenidol), and 200mg kentons@ (tocopherol nicotinate).
|
Drug: 0.25mg, fludiazine
0.25mg of erispan@ (fludiazine), p.o. one dose only.
Other Name: 0.25mg of erispan@
Drug: 25mg cephadol@ (diphenidol)
25mg cephadol@ (diphenidol) p.o. one dose only.
Drug: 200mg kentons@ (tocopherol nicotinate).
200mg kentons@ (tocopherol nicotinate) p.o. one dose only.
|
- SP/AP of Electrocochleography [ Time Frame: ECoG was reorded 2 hours after SGB ]SP/AP of ECoG was recorded 2 hours after SGB. to be compared with the SP/AP of ECoG recorded before treatment
- SP/AP recorded at 4 hours after SGB [ Time Frame: 4 hours after SGB ]SP/AP recorded at 4 hours after SGB was compared with that of pretreatment with SGB
- SP/AP recorded at 6 hours after SGB [ Time Frame: 6 hours after SGB ]SP/AP recorded at 4 hours after SGB was compared with the SP/AP recorded before SGB
- scores of verbal scale for vertigo recorded at 6 hours after SGB [ Time Frame: 6 hours after SGB ]scores of verbal scale for vertigo recorded at 6 hours after SGB was compared to the scores recorded before SGB

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 30 Years to 65 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- patients diagnosed with unilateral Meniere's disease, according to the criteria of the American Academy of Otolaryngology-Head and Neck Surgery, AAO-HNS (1995)
Exclusion Criteria:
- patients with coagulopathy,
- arrhythmia,
- myocardial ischemia,
- glaucoma,
- pregnant,
- chronic otitis media or externa, and
- past history of middle or inner ear surgery were excluded.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01574313
Taiwan | |
i Mei Medical Center Tainan, Taiwan, Taiwan | |
Tainan, Taiwan, 70014 |
Principal Investigator: | Yung-Song Lin, M.D. | Chi Mei Medical Hospital |
Responsible Party: | Yung-Song Lin, Chairman of department of Otolaryngology, Chi Mei Medical Hospital |
ClinicalTrials.gov Identifier: | NCT01574313 History of Changes |
Other Study ID Numbers: |
SGB09804-003 CMH09804-003 ( Other Grant/Funding Number: Chi Mei Medical Center, Taiwan ) |
First Posted: | April 10, 2012 Key Record Dates |
Last Update Posted: | April 11, 2012 |
Last Verified: | April 2012 |
Keywords provided by Yung-Song Lin, Chi Mei Medical Hospital:
stellate ganglion block. Meniere's disease. electrocochleography. vertigo. hearing impairment. |
Additional relevant MeSH terms:
Meniere Disease Ganglion Cysts Vertigo Dizziness Cysts Neoplasms Mucinoses Connective Tissue Diseases Vestibular Diseases Labyrinth Diseases Ear Diseases Otorhinolaryngologic Diseases Neurologic Manifestations Nervous System Diseases Signs and Symptoms |
Sensation Disorders Endolymphatic Hydrops Tocopherols Vitamin E Tocotrienols alpha-Tocopherol Niacin Nicotinic Acids Diphenidol Antioxidants Molecular Mechanisms of Pharmacological Action Protective Agents Physiological Effects of Drugs Vitamins Micronutrients |