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Erythrocyte Complement Receptor 1 and Alzheimer Disease

This study has been completed.
Information provided by (Responsible Party):
CHU de Reims Identifier:
First received: March 26, 2012
Last updated: June 8, 2016
Last verified: March 2012
Main objective: investigate whether a functional polymorphism of CR1 (length, number of binding sites in C4b C3b, erythrocyte density, rate of soluble CR1 ...) so determined genetic or acquired, is a susceptibility factor for the disease Alzheimer's.

Condition Intervention
Alzheimer Disease Other: CR1 impact

Study Type: Interventional
Study Design: Primary Purpose: Screening

Resource links provided by NLM:

Further study details as provided by CHU de Reims:

Enrollment: 200
Study Start Date: February 2012
Study Completion Date: April 2015

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • caucasians people with a Alzheimer dementia defined on DSMIV criteria for patients and without Alzheimer disease for control subjects

Exclusion Criteria:

  • diseases modifying CR1 physiology
  Contacts and Locations
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Please refer to this study by its identifier: NCT01565434

Reims, France, 51092
Sponsors and Collaborators
CHU de Reims
  More Information

Responsible Party: CHU de Reims Identifier: NCT01565434     History of Changes
Other Study ID Numbers: PA11014
Study First Received: March 26, 2012
Last Updated: June 8, 2016

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders processed this record on September 21, 2017