Comparison of Liver and Renal Function After Transarterial Chemoembolization for Primary Hepatocellular Carcinoma With Iso-osmolar Contrast Media and Low Osmolar Contrast Media
|ClinicalTrials.gov Identifier: NCT01563484|
Recruitment Status : Unknown
Verified March 2012 by Li Chen, Southeast University, China.
Recruitment status was: Active, not recruiting
First Posted : March 27, 2012
Last Update Posted : April 2, 2012
|Condition or disease||Phase|
|Primary Hepatocellular Carcinoma||Phase 2 Phase 3|
This was a prospective, randomized, single centre, single-blind study. Patients were randomized (1:1) to use Low-osmolar contrast media or iso-osmolar contrast media for TACE.
On the morning of 2th and 5th days after TACE, a hematologic check was performed, the hematologic check including serum creatinine, blood urea nitrogen, direct bilirubin, indirect bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, lactate dehydrogenase, alkaline phosphatase, cholinesterase. Then, comparing them with the data before TACE.
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Observational Model:||Case Control|
|Official Title:||Comparison of Liver and Renal Function After TACE for PHC With Iso-osmolar and Low-osmolar Contrast Media|
|Study Start Date :||March 2012|
|Estimated Primary Completion Date :||September 2012|
|Estimated Study Completion Date :||September 2012|
low-osmolar contrast media
Patients undergo TACE of low-osmolar contrast media on day 1.
iso-osmolar contrast media
Patients undergo TACE of iso-osmolar contrast media on day 1.
- Change from Baseline in serum creatinine, blood urea nitrogen, direct bilirubin, indirect bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, lactate dehydrogenase, alkaline phosphatase, cholinesterase. [ Time Frame: Follow-up on the 2th and 5th days after TACE ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01563484
|Zhongda Hospital, Southeast University|
|Nanjing, Jiangsu, China, 210009|
|Principal Investigator:||Gao-Jun Teng, MD||Medical School,Southeast University|