Detection of Minimal Change Esophagitis by I-scan
|ClinicalTrials.gov Identifier: NCT01560910|
Recruitment Status : Completed
First Posted : March 22, 2012
Last Update Posted : March 22, 2012
|Condition or disease|
|Gastro-esophageal Reflux Disease Non-erosive Reflux Disease|
Background and aims Majority of patients with gastro-esophageal reflux disease (GERD) were non-erosive reflux disease (NERD). High definition (HD) endoscopy with i-scan could enhance visualization of mucosal and vascular pattern and might identify changes that were invisible at standard endoscopy. This study aimed to evaluate the endoscopic findings that may have diagnostic value for the prediction of NERD by using HD endoscopy with i-scan.
Methods Patients with typical GERD symptoms and healthy control without GERD symptoms were included and 2 validated GERD questionnaires were completed. The endoscopist was blinded to the presence of reflux symptoms and distal esophagus was examined using standard white light endoscopy followed by i-scan. Mucosal morphology at squamocolumnar junction (SCJ) observed by i-scan were compared between GERD patients and controls.
|Study Type :||Observational|
|Actual Enrollment :||48 participants|
|Study Start Date :||January 2010|
|Actual Primary Completion Date :||December 2010|
|Actual Study Completion Date :||December 2010|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01560910
|Maharaj Nakorn Chiangmai Hospital|