Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury

This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2015 by Guangdong General Hospital
Sponsor:
Information provided by (Responsible Party):
Wei Shi, Guangdong General Hospital
ClinicalTrials.gov Identifier:
NCT01560650
First received: March 20, 2012
Last updated: August 19, 2015
Last verified: August 2015
  Purpose

The current international Continuous Renal Replacement Therapy (CRRT) replacement fluid doses of 25 ml/kg/h is better, but the result is according to white people, black people (weight biased towards the data obtained in yellow). It is Whether the best amount of replacement fluid for Chinese people, it is unclear. According to the clinical situation, the design of replacement fluid to 35 ml/kg/h.The observation of two doses 14 days, 28 days, 90 days survival and renal function.


Condition
Acute Kidney Injury

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury: Single-center Randomized Clinical Trial

Further study details as provided by Guangdong General Hospital:

Estimated Enrollment: 300
Study Start Date: March 2011
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: August 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
AKI patients requiring CRRT
> = 18 years of age, CRRT indications for acute kidney injury (RIFLE criteria) patients

Detailed Description:

The investigators will record the demographic characteristics, comorbidities et.al.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

The patients with acute kidney injury need for CRRT in Guangdong General Hospital, Guangzhou,China

Criteria

Inclusion Criteria:

  • > = 18 years of age, CRRT indications for acute kidney injury (RIFLE criteria) patients

Exclusion Criteria:

  • < 18 years old,
  • with chronic kidney disease,
  • dialysis history, to leave the ICU patients with acute kidney injury (AKI). - chronic kidney disease,
  • all causes kidney damage (pathology, hematuria, and radiographic abnormalities)> = 3 months or glomerular filtration rate < 60ml/min for 3 months or more.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01560650

Contacts
Contact: Wei Shi, MD,PhD (86-20)83850849 weishi_gz@126.com

Locations
China, Guangdong
Nephrology Department,Guangdong General Hospital Recruiting
Guangzhou, Guangdong, China
Contact: Xinling Liang, MD,PhD    +86-13808819770    xinlingliang@yahoo.com   
Sponsors and Collaborators
Wei Shi
Investigators
Principal Investigator: Wei Shi, MD, PhD Guangdong General Hospital
  More Information

No publications provided

Responsible Party: Wei Shi, Director of renal division of Guangdong General Hospital, Guangdong General Hospital
ClinicalTrials.gov Identifier: NCT01560650     History of Changes
Other Study ID Numbers: LXL-CRRT2535
Study First Received: March 20, 2012
Last Updated: August 19, 2015
Health Authority: China: Ethics Committee

Keywords provided by Guangdong General Hospital:
CRRT
Acute renal Injury
Intensity

Additional relevant MeSH terms:
Acute Kidney Injury
Kidney Diseases
Renal Insufficiency
Urologic Diseases

ClinicalTrials.gov processed this record on August 31, 2015