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Schistosoma Haematobium Infections and Praziquantel

This study has been completed.
Hikma Pharmaceuticals LLC
Information provided by (Responsible Party):
Ishag Adam, University of Khartoum Identifier:
First received: March 16, 2012
Last updated: January 16, 2013
Last verified: January 2013
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.

Condition Intervention Phase
Drug: praziquantel
Phase 3

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Schistosoma Haematobium Infections Among Schoolchildren in Central Sudan One Year After Treatment With Praziquantel

Resource links provided by NLM:

Further study details as provided by University of Khartoum:

Primary Outcome Measures:
  • cure rate [ Time Frame: one year ]
    The reduction of the prevalence and intensity of S.haematobium infection following a single dose of praziquantel40mg/kg

Secondary Outcome Measures:
  • reduction in the intensity of infection by [ Time Frame: one year ]
    will a single dose of PZQ significantly reduced intensity of infection of S. haematobium infection 1 year after treatment

Enrollment: 520
Study Start Date: August 2008
Study Completion Date: September 2012
Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Praziguantel
tablet single dose
Drug: praziquantel
praziquantel 40 mg/kg oral tablets

Detailed Description:
A longitudinal study will be conducted to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan. A cohort of schoolchildren (6-15 years of age) was investigated before and 1 year after treatment with a single dose of praziquantel 40mg/kg.

Ages Eligible for Study:   6 Years to 15 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • School children

Exclusion Criteria:

  • Taking praziquantel
  Contacts and Locations
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Please refer to this study by its identifier: NCT01558336

Al Salamania
Al Salamania, Nile, Sudan
Sponsors and Collaborators
University of Khartoum
Hikma Pharmaceuticals LLC
  More Information

Responsible Party: Ishag Adam, Professor, University of Khartoum Identifier: NCT01558336     History of Changes
Other Study ID Numbers: Schistosmiasis
Study First Received: March 16, 2012
Last Updated: January 16, 2013

Keywords provided by University of Khartoum:
Schistosoma haematobium
Central Sudan

Additional relevant MeSH terms:
Schistosomiasis haematobia
Trematode Infections
Parasitic Diseases
Urinary Tract Infections
Urologic Diseases
Antiparasitic Agents
Anti-Infective Agents processed this record on April 28, 2017