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Change in Cognitive Function in Obese Patients After Bariatric Surgery - an Observational Study (Obesity)

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Agnes Flöel, Charite University, Berlin, Germany Identifier:
First received: March 13, 2012
Last updated: December 20, 2016
Last verified: December 2016
Bariatric surgery provides a strong and long-term effect in reducing weight in obese subjects. Studies showed that obesity and its comorbidities are associated with a lower cognitive performance. The aim of the researchers study is to examine the cognitive performance of the patients before and after bariatric surgery.

Condition Intervention
Bariatric Surgery
Other: Observation

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Change in Cognitive Function in Obese Patients After Bariatric Surgery - an Observational Study

Resource links provided by NLM:

Further study details as provided by Charite University, Berlin, Germany:

Primary Outcome Measures:
  • performance in a neuropsychological test battery before and after surgery [ Time Frame: 6 month ]

Secondary Outcome Measures:
  • performance in neuropsychological test battery 12 month after surgery compared to performance after 6 month and baseline performance [ Time Frame: 12 month ]
  • performance in further cognitive tests [ Time Frame: 6 - 12 month ]
  • surrogat parameters, blood parameters [ Time Frame: 6-12 month ]

Estimated Enrollment: 64
Study Start Date: August 2011
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: October 2017 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Bariatric Surgery Other: Observation
Observational study to examine changes in cognition following bariatric surgery after one year.


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients from the surgery department of the Charite Universtiy Berlin

Inclusion Criteria:

  • BMI > 40
  • Age: 18-60

Exclusion Criteria:

  • BMI < 40
  • Age < 18 and > 60
  • Presence of Cancer
  • Presence of Chronic Inflammatory Diseases
  • Presence of Addiction
  Contacts and Locations
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Please refer to this study by its identifier: NCT01554228

Surgery Department, Charite University
Berlin, Germany, 10117
Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Agnes Floeel, Prof. MD Charite University, Berlin, Germany
  More Information

Responsible Party: Agnes Flöel, Prof. Dr. med. Agnes Floeel, Charite University, Berlin, Germany Identifier: NCT01554228     History of Changes
Other Study ID Numbers: Obes_Sur_Cog
Study First Received: March 13, 2012
Last Updated: December 20, 2016 processed this record on May 24, 2017