An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01553110|
Recruitment Status : Recruiting
First Posted : March 13, 2012
Last Update Posted : February 23, 2017
|Condition or disease|
|Acute Rhinosinusitis Allergic Rhinitis|
|Study Type :||Observational|
|Estimated Enrollment :||62 participants|
|Official Title:||An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms in Acute Rhinosinusitis.|
|Study Start Date :||March 2012|
|Estimated Primary Completion Date :||February 2018|
|Estimated Study Completion Date :||November 2018|
Male and female subjects 12 years of age and older with acute nasal discharge fewer then 7 days. Patients must be symptomatic at screening.
Male and female subjects of 12 years of age and older with a history suggesting nasal allergic symptoms for at least 1 year. Patients must be symptomatic at screening.
- Nasal Secretion Collection [ Time Frame: 10 minutes ]To measure the biophysical properties of nasal secretions for improved mucus clearance.
- Subjective nasal scoring [ Time Frame: 10 Minutes ]The Sinus and Nasal Quality of Life Survey (SN-20) questionnaire assess the impact of infection on nasal symptoms, emotion, and activity on a scale of worsening symptoms scored 1 through 7 to provide a quantifiable score capable of comparing both disease severity and the impact of interventions on subjective complaints.
- Nasal Volume [ Time Frame: 15 Minutes ]Acoustic rhinometry is used to measure cross-sectional volume of the nasal cavity allowing the calculation of nasal volume.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01553110
|Contact: Meg Lessard, B.S.||email@example.com|
|United States, Virginia|
|Virginia Commonwealth University School of Medicine||Recruiting|
|Richmond, Virginia, United States, 23298|
|Contact: Grace H. Henderson, B.S. 804-628-5875 firstname.lastname@example.org|
|Principal Investigator: Bruce K Rubin, MEngr, MD, MBA, FRCPC|
|Principal Investigator:||Bruce K Rubin, MEngr, MD, MBA, FRCPC||Virginia Commonwealth University School of Medicine|
|Study Director:||Melissa A Yopp, M.S.H.A||Virginia Commonwealth University School of Medicine|