An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms
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|ClinicalTrials.gov Identifier: NCT01553110|
Recruitment Status : Recruiting
First Posted : March 13, 2012
Last Update Posted : March 1, 2018
|Condition or disease|
|Acute Rhinosinusitis Allergic Rhinitis|
|Study Type :||Observational|
|Estimated Enrollment :||62 participants|
|Official Title:||An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms in Acute Rhinosinusitis.|
|Study Start Date :||March 2012|
|Estimated Primary Completion Date :||June 2018|
|Estimated Study Completion Date :||November 2018|
Male and female subjects 12 years of age and older with acute nasal discharge fewer then 7 days. Patients must be symptomatic at screening.
Male and female subjects of 12 years of age and older with a history suggesting nasal allergic symptoms for at least 1 year. Patients must be symptomatic at screening.
- Nasal Secretion Collection [ Time Frame: 10 minutes ]To measure the biophysical properties of nasal secretions for improved mucus clearance.
- Subjective nasal scoring [ Time Frame: 10 Minutes ]The Sinus and Nasal Quality of Life Survey (SN-20) questionnaire assess the impact of infection on nasal symptoms, emotion, and activity on a scale of worsening symptoms scored 1 through 7 to provide a quantifiable score capable of comparing both disease severity and the impact of interventions on subjective complaints.
- Nasal Volume [ Time Frame: 15 Minutes ]Acoustic rhinometry is used to measure cross-sectional volume of the nasal cavity allowing the calculation of nasal volume.
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01553110
|Contact: Meg Lessard, B.S.||firstname.lastname@example.org|
|United States, Virginia|
|Virginia Commonwealth University School of Medicine||Recruiting|
|Richmond, Virginia, United States, 23298|
|Contact: Grace H. Henderson, B.S. 804-628-5875 email@example.com|
|Principal Investigator: Bruce K Rubin, MEngr, MD, MBA, FRCPC|
|Principal Investigator:||Bruce K Rubin, MEngr, MD, MBA, FRCPC||Virginia Commonwealth University School of Medicine|
|Study Director:||Melissa A Yopp, M.S.H.A||Virginia Commonwealth University School of Medicine|