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Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection (CCMOCPAAD)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01552720
Recruitment Status : Unknown
Verified March 2012 by Yang Li, MD, Xijing Hospital.
Recruitment status was:  Recruiting
First Posted : March 13, 2012
Last Update Posted : March 13, 2012
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China. Moreover, clinical characteristics of Acute aortic dissection have not evaluated to data. The aim of this study is analyze changing trend of clinical characteristics of Chinese patients with acute aortic dissection.

Condition or disease
Aortic Dissection

Detailed Description:
Acute aortic dissection is the most common aortic emergency, with an annual incidence of 3-5 cases per 100 000 population. About 50% of these patients are dead within 48 hours, if untreated. To assess the clinical manifestation, diagnosis, management, and outcomes of patients with AAD, the International Registry of Acute Aortic Dissection (IRAD) was established in 1996, and has grown to include about 2000 patients from 26 large referral centers to date. All patients from IRAD are caucasians from developed countries wiht advanced medical care, however, the proportion of Asian is very low. Data reported by the IRAD in not sufficient to reflect clinical characteristics of Acute aortic dissection in China. Clinical characteristics of Chinese patients with acute aortic dissection have not evaluated to data. The aim of this study is to analyze clinical characteristics of Chinese patients with acute aortic dissection and clinical trend of acute aortic dissection.

Study Design

Study Type : Observational
Estimated Enrollment : 5000 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Clinical Investigation of Chinese Patients With Aortic Dissection
Study Start Date : January 2011
Estimated Primary Completion Date : November 2015
Estimated Study Completion Date : December 2015
Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Chinese patients suffering acute aortic dissection
Criteria

Inclusion Criteria:

  • Clinical diagnosis of acute aortic dissection
  • Type A dissection
  • Type B dissection
  • Retrograde type B dissection

Exclusion Criteria:

  • Aortic aneurysm
  • Myocardial infarction
  • Cerebral accident
  • Active infection
  • Unwillingness to cooperation with study procedures or follow-up visits
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01552720


Contacts
Contact: Yang Li, MD 029-6787564 liyangcenter@sina.com

Locations
China, Shaanxi
Xijing Hospital Recruiting
Xi'an, Shaanxi, China, 710032
Contact: Yang Li, MD    029-68574562    liyangcenter@sina.com   
Principal Investigator: Yang Li, MD         
Principal Investigator: Dinghua Yi, PhD,MD         
Principal Investigator: Weixun Duan, MD         
Sponsors and Collaborators
Xijing Hospital
Investigators
Study Director: Dihua Yi, PhD, MD Xijing Hospital
More Information

Additional Information:
Responsible Party: Yang Li, MD, MD, Xijing Hospital
ClinicalTrials.gov Identifier: NCT01552720     History of Changes
Other Study ID Numbers: XJHEART2012
CRAD201203 ( Other Grant/Funding Number: 2011BAI11B00 )
First Posted: March 13, 2012    Key Record Dates
Last Update Posted: March 13, 2012
Last Verified: March 2012

Keywords provided by Yang Li, MD, Xijing Hospital:
aorta
dissection
feature